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• W1578867939 abstract "To characterize diffuse large B-cell lymphoma (DLBCL) with chromosome 7 gains, we combined clinical data with genomic, RNA and miRNA profiling. Gains were associated with age >60 years, female gender, a trend for higher complete response rate, lower death rate, and better overall survival in patients treated with R-CHOP. Lesions were inversely associated with bone marrow involvement and number of extra-nodal sites. Differentially expressed transcripts were enriched of genes belonging to specific pathways and miRNAs targets. MIR96, MIR182, MIR589, MIR25 were shown significantly up-regulated in 7q+ DLBCL by real-time PCR." @default.
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• W1578867939 date "2011-03-21" @default.
• W1578867939 modified "2023-10-16" @default.
• W1578867939 title "Integrated profiling of diffuse large B‐cell lymphoma with 7q gain" @default.
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• W1578867939 doi "https://doi.org/10.1111/j.1365-2141.2011.08628.x" @default.
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