FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1578931418> ?p ?o ?g. }

• W1578931418 endingPage "288" @default.
• W1578931418 startingPage "282" @default.
• W1578931418 abstract "Although data show the importance of type I interferons (IFNs) in the regulation of the innate and adaptive immunity elicited in response to viral, bacterial and parasitic infections, the functional activities of these cytokines during fungal infections are poorly understood. We examined here the impact of IFN-β on the response of human monocyte-derived dendritic cells (DCs) infected in vitro with Aspergillus fumigatus. Having found that A. fumigatus-infected DCs do not express IFN-β, we evaluated the effect of the exogenous addition of IFN-β on the maturation of human DCs induced by the infection with A. fumigatus conidia. Although the phagocytosis of the fungus was not affected by IFN-β treatment, the expression of CD86 and CD83 induced upon A. fumigatus challenge was enhanced in IFN-β-conditioned DCs, which also showed an increased expression of IL-27 and IL-12p70, members of IL-12 family. Through these modifications, IFN-β improved the capacity of DCs to promote an anti-Aspergillus T helper type 1 response, as evaluated by mixed leucocyte reaction, which plays a crucial role in the control of invasive aspergillosis. Our results identified a novel effect of IFN-β on anti-Aspergillus immune responses which, in turn, might open new perspectives on the use of IFN-β in immunotherapy for fungal infections aimed at enhancing the immunological functions of DCs." @default.
• W1578931418 created "2016-06-24" @default.
• W1578931418 creator A5006408418 @default.
• W1578931418 creator A5008417349 @default.
• W1578931418 creator A5030111197 @default.
• W1578931418 creator A5030654574 @default.
• W1578931418 creator A5046674495 @default.
• W1578931418 creator A5054484833 @default.
• W1578931418 date "2010-09-02" @default.
• W1578931418 modified "2023-09-25" @default.
• W1578931418 title "Enhancement of anti-Aspergillus T helper type 1 response by interferon-β-conditioned dendritic cells" @default.
• W1578931418 cites W1482758361 @default.
• W1578931418 cites W1509473864 @default.
• W1578931418 cites W1572283658 @default.
• W1578931418 cites W1649649531 @default.
• W1578931418 cites W1854638296 @default.
• W1578931418 cites W1969446328 @default.
• W1578931418 cites W1981967635 @default.
• W1578931418 cites W1998560756 @default.
• W1578931418 cites W2008102007 @default.
• W1578931418 cites W2008424365 @default.
• W1578931418 cites W2016525911 @default.
• W1578931418 cites W2020538235 @default.
• W1578931418 cites W2021215684 @default.
• W1578931418 cites W2021836393 @default.
• W1578931418 cites W2022986271 @default.
• W1578931418 cites W2034275921 @default.
• W1578931418 cites W2051471157 @default.
• W1578931418 cites W2058315838 @default.
• W1578931418 cites W2061198209 @default.
• W1578931418 cites W2066028474 @default.
• W1578931418 cites W2068111141 @default.
• W1578931418 cites W2077893603 @default.
• W1578931418 cites W2094786750 @default.
• W1578931418 cites W2095276293 @default.
• W1578931418 cites W2095838203 @default.
• W1578931418 cites W2097556922 @default.
• W1578931418 cites W2102252876 @default.
• W1578931418 cites W2107002415 @default.
• W1578931418 cites W2111972223 @default.
• W1578931418 cites W2113606216 @default.
• W1578931418 cites W2121691225 @default.
• W1578931418 cites W2125105493 @default.
• W1578931418 cites W2139002656 @default.
• W1578931418 cites W2139343943 @default.
• W1578931418 cites W2139437304 @default.
• W1578931418 cites W2144013613 @default.
• W1578931418 cites W2153911335 @default.
• W1578931418 cites W2156313733 @default.
• W1578931418 cites W2158452535 @default.
• W1578931418 cites W2165323521 @default.
• W1578931418 cites W2170566395 @default.
• W1578931418 cites W2335230103 @default.
• W1578931418 cites W4211087629 @default.
• W1578931418 cites W4313342413 @default.
• W1578931418 doi "https://doi.org/10.1111/j.1365-2567.2010.03302.x" @default.
• W1578931418 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2967273" @default.
• W1578931418 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20518826" @default.
• W1578931418 hasPublicationYear "2010" @default.
• W1578931418 type Work @default.
• W1578931418 sameAs 1578931418 @default.
• W1578931418 citedByCount "17" @default.
• W1578931418 countsByYear W15789314182012 @default.
• W1578931418 countsByYear W15789314182013 @default.
• W1578931418 countsByYear W15789314182018 @default.
• W1578931418 countsByYear W15789314182019 @default.
• W1578931418 countsByYear W15789314182020 @default.
• W1578931418 countsByYear W15789314182021 @default.
• W1578931418 countsByYear W15789314182022 @default.
• W1578931418 countsByYear W15789314182023 @default.
• W1578931418 crossrefType "journal-article" @default.
• W1578931418 hasAuthorship W1578931418A5006408418 @default.
• W1578931418 hasAuthorship W1578931418A5008417349 @default.
• W1578931418 hasAuthorship W1578931418A5030111197 @default.
• W1578931418 hasAuthorship W1578931418A5030654574 @default.
• W1578931418 hasAuthorship W1578931418A5046674495 @default.
• W1578931418 hasAuthorship W1578931418A5054484833 @default.
• W1578931418 hasBestOaLocation W15789314181 @default.
• W1578931418 hasConcept C136449434 @default.
• W1578931418 hasConcept C160448771 @default.
• W1578931418 hasConcept C193419808 @default.
• W1578931418 hasConcept C203014093 @default.
• W1578931418 hasConcept C2776090121 @default.
• W1578931418 hasConcept C2776178377 @default.
• W1578931418 hasConcept C2779175654 @default.
• W1578931418 hasConcept C2779787849 @default.
• W1578931418 hasConcept C2781101188 @default.
• W1578931418 hasConcept C86803240 @default.
• W1578931418 hasConcept C8891405 @default.
• W1578931418 hasConcept C89423630 @default.
• W1578931418 hasConceptScore W1578931418C136449434 @default.
• W1578931418 hasConceptScore W1578931418C160448771 @default.
• W1578931418 hasConceptScore W1578931418C193419808 @default.
• W1578931418 hasConceptScore W1578931418C203014093 @default.
• W1578931418 hasConceptScore W1578931418C2776090121 @default.
• W1578931418 hasConceptScore W1578931418C2776178377 @default.
• W1578931418 hasConceptScore W1578931418C2779175654 @default.
• W1578931418 hasConceptScore W1578931418C2779787849 @default.

• next