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- W1579454124 abstract "This chapter deals with the current knowledge about Staphylococcus epidermidis. It especially focuses on the pathogenicity of S. epidermidis, the underlying biological properties, and how these properties contrast with those of S. aureus. The brief overview of the disease spectrum is given to place the studies on pathogenesis in perspective. The last part of the chapter deals with one ecological aspect, lantibiotics, which are potentially important for bacterial interference on skin and mucous membranes. Non-aureus staphylococci (NAS), particularly S. epidermidis, are among the most frequently isolated microorganisms in the clinical microbiology laboratory. The most important step in the pathogenesis of S. epidermidis foreign body-associated infectious diseases is the colonization of the polymer surface by the formation of multi-layered cell clusters, which are embedded in an amorphous extracellular material. The relationship of polysaccharide/adhesin (PS/A) to other polysaccharides of S. epidermidis is discussed in the chapter. The establishment of an infection and the survival of the bacteria in the host depend on the ability to invade host tissues and to evade host defense systems, respectively. Although studied in more detail with S. aureus, knowledge about the regulation of S. epidermidis virulence factors has been increased significantly in recent years. Lantibiotics are antibiotic peptides that contain the rare thioether amino acid lanthionine and/or methyllanthionine. Improvement in the armamentarium of molecular methods will enable us to analyze not only the genome but also the proteome of S. epidermidis in the future." @default.
- W1579454124 created "2016-06-24" @default.
- W1579454124 creator A5026896969 @default.
- W1579454124 creator A5055008734 @default.
- W1579454124 date "2014-04-30" @default.
- W1579454124 modified "2023-09-25" @default.
- W1579454124 title "Biology and Pathogenicity of Staphylococcus epidermidis" @default.
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