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- W1579969487 abstract "Background: Airway (AW) complications associated with intubation (IT) and mechanical ventilation (MV) have been observed in preterm infants (PTI).Methods: Fiberbronchoscopy (FB) was performed in symptomatic PTI who were intubated at birth. We describe their clinical manifestations (CM) and FB findings. Chi2 test was used to assess the association between left vocal cord paralysis (LVCP) and patent ductus arteriosus ligation (PDAL). Two logistic regressions were built using “condition likely to be associated with IT and MV (CAIT&MV*)” and “need for tracheostomy” as dependent variables. Gender, gestational age (GA), birth weight (BW), length of IT and PDAL were independent ones.Results: 42 symptomatic PTI underwent a FB: 55% males; age 10±14 mo; GA 27±3 wk; BW 1070±467 gr; IT duration 31±28 d. The most common CM were stridor (76%), dysphonia (38%), failed extubation (12%) and suspicion of upper AW obstruction in lung function tests (12%). AW abnormalities were identified in all PTI: AW malacia (59%), laryngotracheal cyst or granuloma* (45%), LVCP (33%), subglottic stenosis* (30%), supraglottic oedema/hypertrophia* (21%) and tracheal stenosis* (7%). 27 PTI underwent PDAL, 9 tracheostomy and 6 AW surgery. All PTI with LVCP had undergone PDAL (p<0.0001).View this table:Logistic regressionConclusions: All symptomatic PTI had abnormal FB findings. LVCP is strongly associated with PDAL. Each day of invasive MV increases by 9% the risk of acquired AW anomalies and by 6% the need for tracheostomy." @default.
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- W1579969487 date "2011-09-01" @default.
- W1579969487 modified "2023-09-24" @default.
- W1579969487 title "Airway-related complications in preterm infants who were intubated at birth" @default.
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