FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1580054285> ?p ?o ?g. }

• W1580054285 endingPage "1526" @default.
• W1580054285 startingPage "1526" @default.
• W1580054285 abstract "Cerebral vasospasm (CV) remains a significant cause of delayed neurological deficit and ischemic damage after subarachnoid hemorrhage (SAH), despite intensive research effort. The current lack of an effective therapeutic approach is somewhat due to our lack of understanding regarding the mechanism by which this pathological constriction develops. Recent evidence implicates bilirubin oxidation products (BOXes) in the etiology of CV after SAH: BOXes are found in cerebrospinal fluid from SAH patients with symptomatic or angiographically visible vasospasm (CSFV) but not in CSF from SAH patients with no vasospasm (CSFC). We have previously published research suggesting that the etiology of CV comprises two components: a physiological stimulation to constrict and a pathological failure to relax. Both these components are elicited by CSFV, but not CSFC, and BOXes synthesized in the laboratory potentiate physiological constriction in arterial smooth muscle in vitro, and elicit contraction in pial arteries in vivo. In this paper, we will present our results concerning the action of BOXes on arterial smooth muscle constriction, compared with CSFV. We will also present evidence implicating temporal changes in PKC isoforms and Rho expression in both BOXes- and CSFV-elicited smooth muscle responses." @default.
• W1580054285 created "2016-06-24" @default.
• W1580054285 creator A5006724619 @default.
• W1580054285 creator A5019477021 @default.
• W1580054285 creator A5055042810 @default.
• W1580054285 creator A5088399703 @default.
• W1580054285 date "2008-01-01" @default.
• W1580054285 modified "2023-09-27" @default.
• W1580054285 title "PKC and Rho in vascular smooth muscle: Activation by BOXes and SAH CSF" @default.
• W1580054285 cites W1590337053 @default.
• W1580054285 cites W1594129908 @default.
• W1580054285 cites W1594758412 @default.
• W1580054285 cites W1780910759 @default.
• W1580054285 cites W1857294168 @default.
• W1580054285 cites W1970317259 @default.
• W1580054285 cites W1981518609 @default.
• W1580054285 cites W1984555522 @default.
• W1580054285 cites W1986995855 @default.
• W1580054285 cites W1989734551 @default.
• W1580054285 cites W1990794882 @default.
• W1580054285 cites W1993046189 @default.
• W1580054285 cites W1993379452 @default.
• W1580054285 cites W1995814458 @default.
• W1580054285 cites W2002714062 @default.
• W1580054285 cites W2004467890 @default.
• W1580054285 cites W2006872818 @default.
• W1580054285 cites W2009854004 @default.
• W1580054285 cites W2010553121 @default.
• W1580054285 cites W2010820226 @default.
• W1580054285 cites W2011674499 @default.
• W1580054285 cites W2012604018 @default.
• W1580054285 cites W2019121978 @default.
• W1580054285 cites W2022741076 @default.
• W1580054285 cites W2030042069 @default.
• W1580054285 cites W2031365737 @default.
• W1580054285 cites W2034225752 @default.
• W1580054285 cites W2034735445 @default.
• W1580054285 cites W2039642086 @default.
• W1580054285 cites W2041191949 @default.
• W1580054285 cites W2041408973 @default.
• W1580054285 cites W2047720109 @default.
• W1580054285 cites W2048594266 @default.
• W1580054285 cites W2049973124 @default.
• W1580054285 cites W2058775391 @default.
• W1580054285 cites W2060885544 @default.
• W1580054285 cites W2061229883 @default.
• W1580054285 cites W2077298757 @default.
• W1580054285 cites W2095567957 @default.
• W1580054285 cites W2099733311 @default.
• W1580054285 cites W2105858933 @default.
• W1580054285 cites W2108387989 @default.
• W1580054285 cites W2109358726 @default.
• W1580054285 cites W2115963705 @default.
• W1580054285 cites W2118005681 @default.
• W1580054285 cites W2119416030 @default.
• W1580054285 cites W2122053013 @default.
• W1580054285 cites W2130406955 @default.
• W1580054285 cites W2134603143 @default.
• W1580054285 cites W2147563392 @default.
• W1580054285 cites W2160207920 @default.
• W1580054285 cites W2160864876 @default.
• W1580054285 cites W2163685403 @default.
• W1580054285 cites W2171291238 @default.
• W1580054285 cites W2180746786 @default.
• W1580054285 cites W2235565765 @default.
• W1580054285 cites W2268218687 @default.
• W1580054285 cites W2292532100 @default.
• W1580054285 cites W2297688515 @default.
• W1580054285 cites W2409409622 @default.
• W1580054285 cites W2410761444 @default.
• W1580054285 cites W2419315415 @default.
• W1580054285 cites W52268341 @default.
• W1580054285 cites W58320878 @default.
• W1580054285 doi "https://doi.org/10.2741/2778" @default.
• W1580054285 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2430991" @default.
• W1580054285 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17981646" @default.
• W1580054285 hasPublicationYear "2008" @default.
• W1580054285 type Work @default.
• W1580054285 sameAs 1580054285 @default.
• W1580054285 citedByCount "14" @default.
• W1580054285 countsByYear W15800542852012 @default.
• W1580054285 countsByYear W15800542852013 @default.
• W1580054285 countsByYear W15800542852014 @default.
• W1580054285 countsByYear W15800542852015 @default.
• W1580054285 countsByYear W15800542852018 @default.
• W1580054285 countsByYear W15800542852022 @default.
• W1580054285 crossrefType "journal-article" @default.
• W1580054285 hasAuthorship W1580054285A5006724619 @default.
• W1580054285 hasAuthorship W1580054285A5019477021 @default.
• W1580054285 hasAuthorship W1580054285A5055042810 @default.
• W1580054285 hasAuthorship W1580054285A5088399703 @default.
• W1580054285 hasBestOaLocation W15800542851 @default.
• W1580054285 hasConcept C126322002 @default.
• W1580054285 hasConcept C137627325 @default.
• W1580054285 hasConcept C163415756 @default.
• W1580054285 hasConcept C164705383 @default.
• W1580054285 hasConcept C171614378 @default.
• W1580054285 hasConcept C174940676 @default.

• next