FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1580347875> ?p ?o ?g. }

• W1580347875 endingPage "1054" @default.
• W1580347875 startingPage "1042" @default.
• W1580347875 abstract "Being able to predict preterm birth is important, as it may allow a high-risk population to be selected for future interventional studies and help in understanding the pathways that lead to preterm birth.To investigate the accuracy of novel biomarkers to predict spontaneous preterm birth in women with singleton pregnancies and no symptoms of preterm labour.Electronic searches in PubMed, Embase, Cinahl, Lilacs, and Medion, references of retrieved articles, and conference proceedings. No language restrictions were applied.Observational studies that evaluated the accuracy of biomarkers proposed in the last decade to predict spontaneous preterm birth in asymptomatic women. We excluded studies in which biomarkers were evaluated in women with preterm labour.Two reviewers independently extracted data on study characteristics, quality, and accuracy. Data were arranged in 2 × 2 contingency tables and synthesised separately for spontaneous preterm birth before 32, 34, and 37 weeks of gestation. We used bivariate meta-analysis to estimate pooled sensitivities and specificities, and calculated likelihood ratios (LRs).A total of 72 studies, including 89,786 women and evaluating 30 novel biomarkers, met the inclusion criteria. Only three biomarkers (proteome profile and prolactin in cervicovaginal fluid, and matrix metalloproteinase-8 in amniotic fluid) had positive LRs > 10. However, each of these biomarkers was evaluated in only one small study. Four biomarkers had a moderate predictive accuracy (interleukin-6 and angiogenin, in amniotic fluid; human chorionic gonadotrophin and phosphorylated insulin-like growth factor binding protein-1, in cervicovaginal fluid). The remaining biomarkers had low predictive accuracies.None of the biomarkers evaluated in this review meet the criteria to be considered a clinically useful test to predict spontaneous preterm birth. Further large, prospective cohort studies are needed to evaluate promising biomarkers such as a proteome profile in cervicovaginal fluid." @default.
• W1580347875 created "2016-06-24" @default.
• W1580347875 creator A5037762715 @default.
• W1580347875 creator A5039160245 @default.
• W1580347875 creator A5047762193 @default.
• W1580347875 creator A5050833142 @default.
• W1580347875 date "2011-03-15" @default.
• W1580347875 modified "2023-10-16" @default.
• W1580347875 title "Novel biomarkers for the prediction of the spontaneous preterm birth phenotype: a systematic review and meta-analysis" @default.
• W1580347875 cites W1509683953 @default.
• W1580347875 cites W1518545792 @default.
• W1580347875 cites W1570510424 @default.
• W1580347875 cites W180297847 @default.
• W1580347875 cites W1850249898 @default.
• W1580347875 cites W1963975423 @default.
• W1580347875 cites W1965523766 @default.
• W1580347875 cites W1966399531 @default.
• W1580347875 cites W1967009232 @default.
• W1580347875 cites W1967485323 @default.
• W1580347875 cites W1971348077 @default.
• W1580347875 cites W1973430946 @default.
• W1580347875 cites W1973557139 @default.
• W1580347875 cites W1973593314 @default.
• W1580347875 cites W1974972919 @default.
• W1580347875 cites W1975286285 @default.
• W1580347875 cites W1975755498 @default.
• W1580347875 cites W1975875877 @default.
• W1580347875 cites W1976376842 @default.
• W1580347875 cites W1977203954 @default.
• W1580347875 cites W1980936535 @default.
• W1580347875 cites W1981445452 @default.
• W1580347875 cites W1981476253 @default.
• W1580347875 cites W1992226857 @default.
• W1580347875 cites W1995988370 @default.
• W1580347875 cites W1998688542 @default.
• W1580347875 cites W2006905636 @default.
• W1580347875 cites W2008029664 @default.
• W1580347875 cites W2009636332 @default.
• W1580347875 cites W2012116364 @default.
• W1580347875 cites W2012265893 @default.
• W1580347875 cites W2014987252 @default.
• W1580347875 cites W2015106832 @default.
• W1580347875 cites W2020744881 @default.
• W1580347875 cites W2021644203 @default.
• W1580347875 cites W2024116038 @default.
• W1580347875 cites W2025420713 @default.
• W1580347875 cites W2025797556 @default.
• W1580347875 cites W2026152054 @default.
• W1580347875 cites W2027143713 @default.
• W1580347875 cites W2030674238 @default.
• W1580347875 cites W2031456677 @default.
• W1580347875 cites W2031466412 @default.
• W1580347875 cites W2032256710 @default.
• W1580347875 cites W2033082800 @default.
• W1580347875 cites W2036540680 @default.
• W1580347875 cites W2036771593 @default.
• W1580347875 cites W2043517504 @default.
• W1580347875 cites W2045280844 @default.
• W1580347875 cites W2045560017 @default.
• W1580347875 cites W2046629177 @default.
• W1580347875 cites W2047075436 @default.
• W1580347875 cites W2049781796 @default.
• W1580347875 cites W2051868855 @default.
• W1580347875 cites W2054162471 @default.
• W1580347875 cites W2057110751 @default.
• W1580347875 cites W2057443365 @default.
• W1580347875 cites W2058212817 @default.
• W1580347875 cites W2059200111 @default.
• W1580347875 cites W2062481654 @default.
• W1580347875 cites W2064710131 @default.
• W1580347875 cites W2068609622 @default.
• W1580347875 cites W2070173049 @default.
• W1580347875 cites W2070996185 @default.
• W1580347875 cites W2076325059 @default.
• W1580347875 cites W2077772616 @default.
• W1580347875 cites W2078169308 @default.
• W1580347875 cites W2079737158 @default.
• W1580347875 cites W2085835557 @default.
• W1580347875 cites W2086091484 @default.
• W1580347875 cites W2089478776 @default.
• W1580347875 cites W2095908334 @default.
• W1580347875 cites W2097737765 @default.
• W1580347875 cites W2097947795 @default.
• W1580347875 cites W2099863561 @default.
• W1580347875 cites W2100280977 @default.
• W1580347875 cites W2103357639 @default.
• W1580347875 cites W2108898326 @default.
• W1580347875 cites W2116573834 @default.
• W1580347875 cites W2118006745 @default.
• W1580347875 cites W2119297241 @default.
• W1580347875 cites W2125435699 @default.
• W1580347875 cites W2126727011 @default.
• W1580347875 cites W2127510146 @default.
• W1580347875 cites W2128897404 @default.
• W1580347875 cites W2129124381 @default.
• W1580347875 cites W2129152887 @default.
• W1580347875 cites W2133250990 @default.
• W1580347875 cites W2140245346 @default.

• next