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- W1580621471 abstract "Serum testosterone (T) concentrations, measured by a specific, precise, and sensitive radioimmunoassay in 40 women with apparently normal menstrual cycles averaged 34.6 ± 10.3 (S.D.) ng. per cent and ranged from 14 to 59 ng. per cent. Mean serum T concentrations, assayed daily in eight women throughout an entire ovulatory cycle, were highest around the midcycle LH peak and higher during the follicular than during the luteal phase of the cycles. Averages of daily serum T concentrations, when determined for each individual woman for the entire cycle, varied significantly among the eight subjects studied, ranging from 23.1 to 39.0 ng. per cent. Coefficients of variation of serum T levels in these eight individual cycles averaged 22 per cent. HCG administration to three of these eight women during the luteal phase of their subsequent cycle resulted in a significant rise of serum T concentrations in only one subject. These data indicate that mean serum T concentrations in normal women are subject to small but significant changes during the course of the menstrual cycle. Despite these cyclic changes, as well as day-to-day variations, serum T concentrations in normal women largely fall into a relatively narrow range. Repeated serum T concentrations which consistently exceed 55 ng. per cent (2 S.D. above the mean) may be regarded as documentation of androgen excess." @default.
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- W1580621471 date "1974-06-01" @default.
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- W1580621471 title "Serum testosterone concentrations in women throughout the menstrual cycle and following HCG administration" @default.
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- W1580621471 doi "https://doi.org/10.1016/0002-9378(74)90199-9" @default.
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