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• W1580734725 abstract "Visceral fat accumulation is associated with several changes, such as, increased production of inflammatory biomarkers, especially, C-reactive protein (CRP) and fibrinogen. Anthropometric measurements for central adiposity evaluation, such as, waist circumference (WC) and sagittal abdominal diameter (SAD) have been highlighted. However, there is no consensus on the best anatomical site for measurement.To evaluate the reliability of different measurements of WC and SAD and verify their capacity to discriminate changes in inflammatory biomarkers.130 men (20-59 years) were assessed, having measurements of weight, height, WC and SAD. It was considered as the cutoff point for high-sensitivity CRP (hs-CRP) values ≥ 0.12 mg/dL and for fibrinogen the 50th percentile of the evaluated sample.All measurements presented an intraclass correlation coefficient between 0.998 and 0.999. WC measured at the umbilical level (AUC=0.693 ± 0.049) and the smallest circumference between the thorax and the hips (AUC=0.607 ± 0.050) had greater ability to discriminate changes in concentrations of hs-CRP and fibrinogen, respectively. SAD (umbilical level) showed the better ability to detect changes in concentrations of hs-CRP (AUC=0.698 ± 0.049) and fibrinogen (AUC=0.625 ± 0.049), according to the ROC analysis (p<0.05).WC (smallest circumference between the thorax and the hips) and SAD (umbilical level) are the anatomic sites of measurement for use in predicting the inflammatory risk in apparently health men.La acumulacion de grasa visceral se asocia con varios cambios, tales como, aumento de la produccion de los biomarcadores inflamatorios, en especial, la proteina C-reactiva (PCR) y fibrinogeno. Las medidas antropometricas para la evaluacion de la adiposidad central, como la circunferencia de la cintura (CC) y el diametro abdominal sagital (DAS) se han destacado. Sin embargo, no hay consenso sobre el mejor sitio anatomico para la medicion.Evaluar la fiabilidad de diferentes mediciones de CC y DAS y verificar su capacidad para discriminar los cambios en biomarcadores inflamatorios.Se evaluaron 130 hombres (20-59 anos). Se midio peso, estatura, circunferencia de la cintura (CC) y diametro abdominal sagital (DAS). Se considero como punto de corte para los valores de PCR ultrasensible (PCR-us) ≥ 0,12 mg/dL y para el fibrinogeno se utilizo el percentil 50 de la muestra evaluada.Todas las mediciones presentaron un coeficiente de correlacion intraclase entre 0.998 y 0.999. CC medida a nivel umbilical (AUC=0,693}0,049) y la circunferencia mas pequena entre el torax y las caderas (AUC=0,607}0,050) tuvieron una mayor capacidad para discriminar los cambios en las concentraciones de PCRus y fibrinogeno, respectivamente. DAS (nivel umbilical) mostro la mejor capacidad para detectar cambios en las concentraciones de PCR-us (AUC=0,698}0,049) y fibrinogeno (AUC=0,625}0,049), de acuerdo con el analisis ROC (p." @default.
• W1580734725 created "2016-06-24" @default.
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• W1580734725 date "2014-09-01" @default.
• W1580734725 modified "2023-09-23" @default.
• W1580734725 title "Relationship between waist circumference and sagittal abdominal diameter measured at different anatomical sites and inflammatory biomarkers in apparently health men." @default.
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• W1580734725 doi "https://doi.org/10.3305/nh.2014.30.3.7534" @default.
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