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• W1581452902 abstract "Aim: The aim of this study was to estimate the prevalence of apathy, and to compare vascular mild cognitive impairment ( vMCI ), amnestic MCI ( amMCI ), and other type using Clinical Assessment for Spontaneity ( CAS ). Methods: Agreement to take part in the study was obtained from 590 community dwellers, aged ≥75 years living in K urihara, J apan. Of the 590 subjects, 221 had a clinical dementia rating ( CDR ) of 0 (normal); 295 had CDR 0.5 (mild cognitive impairment; MCI ); and 74 had CDR 1+ (dementia). The CDR 0.5 subjects were divided into three groups: 55 with vMCI ( E rkinjuntti et al . criteria), 91 with amMCI and 149 with other type. To evaluate the various aspects of apathy, we used the three CAS subscales: clinical interview ( CAS 1), self‐evaluation ( CAS 2), and caregiver assessment ( CAS 3). Three analyses were then performed to determine: (i) the validity of CAS ; (ii) the prevalence rate of apathy in CDR 0 versus CDR 0.5 versus CDR 1+; and (iii) the prevalence rate of apathy in normal versus vMCI versus amMCI versus other type. Results: CAS was validated with the A pathy E valuation S cale. There were significant differences among the three CDR groups in CAS 1, CAS 2 and CAS 3 ( P < 0.001). The prevalence rate of apathy in each CAS in the CDR 1+ group was higher than the CDR 0.5 group, which was higher than the CDR 0 group. There was a significant difference in CAS 3 score between the four groups (the normal and the three subgroups; P < 0.001). Apathy in vMCI was more severe than in the other three groups ( P < 0.05) on CAS 3 score. Conclusions: vMCI subjects have more severe apathy compared with amMCI subjects on caregiver assessment." @default.
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• W1581452902 date "2013-10-22" @default.
• W1581452902 modified "2023-09-30" @default.
• W1581452902 title "Apathy is more severe in vascular than amnestic mild cognitive impairment in a community: The Kurihara Project" @default.
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• W1581452902 doi "https://doi.org/10.1111/pcn.12098" @default.
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