FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W158160444> ?p ?o ?g. }

• W158160444 endingPage "45" @default.
• W158160444 startingPage "39" @default.
• W158160444 abstract "Secretion of the gut hormone glucagon-like peptide-1 (GLP-1) is stimulated by meal ingestion. The response is rapid, suggesting a stimulatory pathway elicited from the upper gastrointestinal area. In pigs, we have been unable to demonstrate a neural stimulatory pathway, but GLP-1 secretion is regulated by local somatostatin secretion. In search for an endocrine pathway, we studied the effect of a range of concentrations of cholecystokinin octapeptide (26-33) (CCK 8), gastric inhibitory peptide 1-42 (GIP), secretin, motilin, calcitonin gene-related peptide (CGRP), and the modified amino acid, 5-hydroxytryptamine (serotonin, 5-HT) on GLP-1 and somatostatin release from isolated perfused segments of porcine ileum.GLP-1 secretion was stimulated by 1 nM CCK 8 and 10 nM GIP, but suppressed by 1 nM motilin and 1 microM 5-HT. Secretin and CGRP had no effect. Somatostatin secretion was stimulated by CCK 8 at 1 and 10 nM, by GIP at 1 and 10 nM and by 10 nM CGRP. Secretin, 5-HT and motilin had no effect on somatostatin secretion. We conclude that CCK 8 and GIP 1-42 stimulated GLP-1 secretion, but only in concentrations greatly exceeding normal postprandial concentrations. Thus, we find it unlikely that endocrine agents from the duodenum regulate GLP-1 secretion in pigs." @default.
• W158160444 created "2016-06-24" @default.
• W158160444 creator A5060473289 @default.
• W158160444 creator A5085434984 @default.
• W158160444 date "2002-12-01" @default.
• W158160444 modified "2023-10-15" @default.
• W158160444 title "The effects of duodenal peptides on glucagon-like peptide-1 secretion from the ileum" @default.
• W158160444 cites W1237155366 @default.
• W158160444 cites W1482009781 @default.
• W158160444 cites W1967182756 @default.
• W158160444 cites W1969932276 @default.
• W158160444 cites W2007757049 @default.
• W158160444 cites W2010139988 @default.
• W158160444 cites W2010299624 @default.
• W158160444 cites W2019734642 @default.
• W158160444 cites W2022227749 @default.
• W158160444 cites W2028558122 @default.
• W158160444 cites W2035530115 @default.
• W158160444 cites W2041150765 @default.
• W158160444 cites W2041562519 @default.
• W158160444 cites W2064492226 @default.
• W158160444 cites W2067651780 @default.
• W158160444 cites W2072253482 @default.
• W158160444 cites W2072494899 @default.
• W158160444 cites W2080128749 @default.
• W158160444 cites W2087063469 @default.
• W158160444 cites W2094058104 @default.
• W158160444 cites W2119987208 @default.
• W158160444 cites W2154796281 @default.
• W158160444 cites W2175016966 @default.
• W158160444 cites W4232782643 @default.
• W158160444 cites W4233330545 @default.
• W158160444 cites W4236588095 @default.
• W158160444 cites W4243689828 @default.
• W158160444 cites W4246361114 @default.
• W158160444 cites W4252292585 @default.
• W158160444 doi "https://doi.org/10.1016/s0167-0115(02)00157-x" @default.
• W158160444 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12468108" @default.
• W158160444 hasPublicationYear "2002" @default.
• W158160444 type Work @default.
• W158160444 sameAs 158160444 @default.
• W158160444 citedByCount "69" @default.
• W158160444 countsByYear W1581604442012 @default.
• W158160444 countsByYear W1581604442013 @default.
• W158160444 countsByYear W1581604442014 @default.
• W158160444 countsByYear W1581604442015 @default.
• W158160444 countsByYear W1581604442016 @default.
• W158160444 countsByYear W1581604442017 @default.
• W158160444 countsByYear W1581604442018 @default.
• W158160444 countsByYear W1581604442019 @default.
• W158160444 countsByYear W1581604442020 @default.
• W158160444 countsByYear W1581604442021 @default.
• W158160444 countsByYear W1581604442022 @default.
• W158160444 crossrefType "journal-article" @default.
• W158160444 hasAuthorship W158160444A5060473289 @default.
• W158160444 hasAuthorship W158160444A5085434984 @default.
• W158160444 hasConcept C103395026 @default.
• W158160444 hasConcept C118303440 @default.
• W158160444 hasConcept C126322002 @default.
• W158160444 hasConcept C131793682 @default.
• W158160444 hasConcept C134018914 @default.
• W158160444 hasConcept C163170386 @default.
• W158160444 hasConcept C170493617 @default.
• W158160444 hasConcept C185592680 @default.
• W158160444 hasConcept C2776129832 @default.
• W158160444 hasConcept C2776297358 @default.
• W158160444 hasConcept C2776398474 @default.
• W158160444 hasConcept C2777180221 @default.
• W158160444 hasConcept C2777226302 @default.
• W158160444 hasConcept C2777593968 @default.
• W158160444 hasConcept C2777951760 @default.
• W158160444 hasConcept C2778563252 @default.
• W158160444 hasConcept C2778677841 @default.
• W158160444 hasConcept C2779627488 @default.
• W158160444 hasConcept C2780796126 @default.
• W158160444 hasConcept C46699223 @default.
• W158160444 hasConcept C49039625 @default.
• W158160444 hasConcept C555293320 @default.
• W158160444 hasConcept C56191518 @default.
• W158160444 hasConcept C71315377 @default.
• W158160444 hasConcept C71924100 @default.
• W158160444 hasConcept C86803240 @default.
• W158160444 hasConcept C93984277 @default.
• W158160444 hasConceptScore W158160444C103395026 @default.
• W158160444 hasConceptScore W158160444C118303440 @default.
• W158160444 hasConceptScore W158160444C126322002 @default.
• W158160444 hasConceptScore W158160444C131793682 @default.
• W158160444 hasConceptScore W158160444C134018914 @default.
• W158160444 hasConceptScore W158160444C163170386 @default.
• W158160444 hasConceptScore W158160444C170493617 @default.
• W158160444 hasConceptScore W158160444C185592680 @default.
• W158160444 hasConceptScore W158160444C2776129832 @default.
• W158160444 hasConceptScore W158160444C2776297358 @default.
• W158160444 hasConceptScore W158160444C2776398474 @default.
• W158160444 hasConceptScore W158160444C2777180221 @default.
• W158160444 hasConceptScore W158160444C2777226302 @default.
• W158160444 hasConceptScore W158160444C2777593968 @default.
• W158160444 hasConceptScore W158160444C2777951760 @default.

• next