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• W1581941569 abstract "Since the first application of CT angiography (CTA) for the diagnosis of acute pulmonary embolism (PE) in the early nineties (1), CTA has become the first imaging technique of choice in the workup of patients with suspected PE. Though the considerable inherent limitations of CTA with single-detector CT (SDCT) systems, its diagnostic potential for direct visualization of arterial clots was instantaneously appreciated by the radiological community. Limited by a maximum breath hold of 30 s and a single detector row data acquisition, image quality and thus diagnostic efficiency was limited by the trade off between the need to cover a certain scan length and the spatial resolution determined by the slice collimation: e .g., with a slice collimation of 5 mm only a scan range of 15 cm could be covered within 30 s. Even with use of 3 mm collimation and a pitch of 1.7, a confident detection of acute PE was only possible down to the segmental level. With the newest generation CT scanners the full chest can be scanned in less than 4 s with sub-millimeter collimation which has become the standard nowadays (see table 1). Small thrombi can be identified in subsegmental arterial branches and elaborate post-processing techniques can be executed, resulting in a significant increase of both sensitivity and specificity in PE detection. This substantial gain in image acquisition speed and spatial resolution also lead to novel image interpretation concepts including the assessment of perfusion defects of the lung parenchyma and the evaluation of cardiac dysfunction, both of which are important determinants for the clinical outcome of the patient. Besides the significant increase of detectors in the most recent generations of CT scanners a complete novel concept has been developed: dual-source CT. Although the main gain of the use of two radiation sources is the steep increase in temporal resolution, which is especially of benefit for cardiac scanning, this new technique can also be used for PE detection by performing either a dual-source CT protocol resulting in CTA and CT perfusion datasets obtained during one image acquisition, or as a fast track protocol resulting in a dataset obtained within 1 s and without disturbing breathing artifacts, even in very dyspnoeic patients." @default.
• W1581941569 created "2016-06-24" @default.
• W1581941569 creator A5030141337 @default.
• W1581941569 creator A5037325327 @default.
• W1581941569 creator A5088631874 @default.
• W1581941569 date "2011-09-30" @default.
• W1581941569 modified "2023-10-18" @default.
• W1581941569 title "State-of-the-Art Multi-Detector CT Angiography in Acute Pulmonary Embolism: Technique, Interpretation and Future Perspectives" @default.
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• W1581941569 doi "https://doi.org/10.5772/22763" @default.
• W1581941569 hasPublicationYear "2011" @default.
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