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- W1582012670 abstract "Un homme de 49 ans reçoit, pour une hypertension artérielle, une dose orale quotidienne d'acébutolol de 800 mg à 1 g pendant 13 mois. Au bout de ce délai, il présente un épisode respiratoire ayant tous les caractères cliniques, radiologiques et fonctionnels respiratoires d'une pneumopathie d'hypersensibilité. Le liquide de lavage bronchoalvéolaire comporte une lymphocytose et un rapport inversé des sous-populations lymphocytaires. Le test d'inhibition de la migration des leucocytes du malade est positif en présence de faibles concentrations d'acébutolol. Aucune autre cause de pneumopathie n'est décelable. 3 semaines après l'arrêt de ce médicament, tous les signes ou symptômes anormaux ont disparu ou se sont amendés. Les caractéristiques du liquide de lavage alvéolaire, la positivité du TIML et l'évolution sont les trois arguments du diagnostic de pneumopathic d'hypersensibilité à l'acébutolol. A 49 year old man suffering from high blood pressure was treated with a daily dose of from 800 mg to 1 g of acebutolol for 13 months. At the end of this period, he had a respiratory attack with all of the clinical, radiological and functional signs of pneumopathy resulting from hypersensitivity. The bronchioalveolar washing fluid revealed lymphocytosis and a reverse ratio of lymphocytic subpopulations. The patient's leukocyte migration inhibition test was positive in the presence of low concentrations of acebutolol. No other cause of pneumopathy was detected. 3 weeks after termination of treatment, all abnormal signs or symptoms either disappeared or improved. The characteristics of the alveolar washing fluid, the positive leukocyte migration inhibition test and the evolution support the diagnosis of pneumoathy resulting from hypersensitivity to acebutolol." @default.
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- W1582012670 date "1985-04-01" @default.
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- W1582012670 title "Pneumopathie d'hypersensibilité à l'acébutolol" @default.
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- W1582012670 doi "https://doi.org/10.1016/s0335-7457(85)80044-7" @default.
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