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- W1582783608 abstract "The methods of dextran gel filtration and membrane dialysis were utilized to demonstrate the small amount of in vivo human serum protein binding of tritiated digoxin. The biologic and radioactive serum half-time, metabolism, low serum level, short duration of action, and excretion of the glycoside correlate with the lack of significant serum protein binding shown in these experiments with tritiated digoxin. Protein binding of digoxin also is important in the enterohepatic recycling of digoxin since lack of protein binding (1 to 10 percent) and lack of recycling (6.8 percent) appear to be related to the polar structure of the glycoside." @default.
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- W1582783608 date "1971-09-01" @default.
- W1582783608 modified "2023-10-09" @default.
- W1582783608 title "Tritiated digoxin" @default.
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- W1582783608 doi "https://doi.org/10.1016/0002-9149(71)90122-6" @default.
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