Matches in SemOpenAlex for { <https://semopenalex.org/work/W1582923458> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W1582923458 abstract "Rosacea is a chronic inflammatory condition of facial skin estimated to affect more than 16 million Americans. Although the pathogenesis of rosacea is not fully understood, recent evidence in vitro as well as in vivo has supported the role of increased levels of the trypsin-like serine protease, kallikrein 5, in initiating an augmented inflammatory response in rosacea. The increase in the quantity and magnitude of biological activity of kallikrein 5 leads to production of greater quantities of cathelicidin (LL-37), an antimicrobial peptide associated with increases in innate cutaneous inflammation, vasodilation, and vascular proliferation, all of which are characteristic features of rosacea. In this article, the authors review the literature supporting the role of kallikrein 5 in the pathophysiology of rosacea, including how therapeutic interventions modulate the effects of kallikrein 5, thus providing further support for this pathophysiological model that at least partially explains many of the clinical features of cutaneous rosacea." @default.
- W1582923458 created "2016-06-24" @default.
- W1582923458 creator A5007581860 @default.
- W1582923458 creator A5056015339 @default.
- W1582923458 date "2014-01-01" @default.
- W1582923458 modified "2023-09-26" @default.
- W1582923458 title "Kallikrein 5-mediated inflammation in rosacea: clinically relevant correlations with acute and chronic manifestations in rosacea and how individual treatments may provide therapeutic benefit." @default.
- W1582923458 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3930536" @default.
- W1582923458 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24563692" @default.
- W1582923458 hasPublicationYear "2014" @default.
- W1582923458 type Work @default.
- W1582923458 sameAs 1582923458 @default.
- W1582923458 citedByCount "11" @default.
- W1582923458 countsByYear W15829234582016 @default.
- W1582923458 countsByYear W15829234582017 @default.
- W1582923458 countsByYear W15829234582018 @default.
- W1582923458 countsByYear W15829234582020 @default.
- W1582923458 countsByYear W15829234582021 @default.
- W1582923458 countsByYear W15829234582022 @default.
- W1582923458 crossrefType "journal-article" @default.
- W1582923458 hasAuthorship W1582923458A5007581860 @default.
- W1582923458 hasAuthorship W1582923458A5056015339 @default.
- W1582923458 hasConcept C16005928 @default.
- W1582923458 hasConcept C2777673923 @default.
- W1582923458 hasConcept C2778081122 @default.
- W1582923458 hasConcept C2778847519 @default.
- W1582923458 hasConcept C2779121184 @default.
- W1582923458 hasConcept C2780485487 @default.
- W1582923458 hasConcept C2908647359 @default.
- W1582923458 hasConcept C71924100 @default.
- W1582923458 hasConcept C99454951 @default.
- W1582923458 hasConceptScore W1582923458C16005928 @default.
- W1582923458 hasConceptScore W1582923458C2777673923 @default.
- W1582923458 hasConceptScore W1582923458C2778081122 @default.
- W1582923458 hasConceptScore W1582923458C2778847519 @default.
- W1582923458 hasConceptScore W1582923458C2779121184 @default.
- W1582923458 hasConceptScore W1582923458C2780485487 @default.
- W1582923458 hasConceptScore W1582923458C2908647359 @default.
- W1582923458 hasConceptScore W1582923458C71924100 @default.
- W1582923458 hasConceptScore W1582923458C99454951 @default.
- W1582923458 hasLocation W15829234581 @default.
- W1582923458 hasOpenAccess W1582923458 @default.
- W1582923458 hasPrimaryLocation W15829234581 @default.
- W1582923458 hasRelatedWork W1979258089 @default.
- W1582923458 hasRelatedWork W2025374951 @default.
- W1582923458 hasRelatedWork W2027534061 @default.
- W1582923458 hasRelatedWork W2053870595 @default.
- W1582923458 hasRelatedWork W2065076197 @default.
- W1582923458 hasRelatedWork W2068044240 @default.
- W1582923458 hasRelatedWork W2111477301 @default.
- W1582923458 hasRelatedWork W2288175659 @default.
- W1582923458 hasRelatedWork W2464964570 @default.
- W1582923458 hasRelatedWork W2472797931 @default.
- W1582923458 hasRelatedWork W2474289626 @default.
- W1582923458 hasRelatedWork W2483252832 @default.
- W1582923458 hasRelatedWork W2520114368 @default.
- W1582923458 hasRelatedWork W2902713005 @default.
- W1582923458 hasRelatedWork W2944086152 @default.
- W1582923458 hasRelatedWork W3004389862 @default.
- W1582923458 hasRelatedWork W3028692357 @default.
- W1582923458 hasRelatedWork W3091356894 @default.
- W1582923458 hasRelatedWork W3196588569 @default.
- W1582923458 hasRelatedWork W2895385422 @default.
- W1582923458 isParatext "false" @default.
- W1582923458 isRetracted "false" @default.
- W1582923458 magId "1582923458" @default.
- W1582923458 workType "article" @default.