FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1583083639> ?p ?o ?g. }

• W1583083639 endingPage "58" @default.
• W1583083639 startingPage "349" @default.
• W1583083639 abstract "Angiogenesis is an essential event in the development of synovial inflammation in rheumatoid arthritis (RA). The aim of the current study was to investigate the expression of vasohibin-1, a novel endothelium-derived vascular endothelial growth factor (VEGF)-inducible angiogenesis inhibitor, in the RA synovium, and to test the effect of inflammatory cytokines on the expression of vasohibin-1 by RA synovial fibroblasts (RASFs). Synovial tissue samples were obtained at surgery from patients with osteoarthritis (OA) and RA, and subjected to immunohistochemistry to investigate the expression and distribution of vasohibin-1 relevant to the degree of synovial inflammation. In an in vitro analysis, RASFs were used to examine the expression of vasohibin-1 and VEGF mRNA by real-time PCR after stimulation with VEGF or inflammatory cytokines under normoxic or hypoxic conditions. The immunohistochemical results showed that vasohibin-1 was expressed in synovial lining cells, endothelial cells, and synovial fibroblasts. In synovial tissue, there was a significant correlation between the expression of vasohibin-1 and histological inflammation score (p=0.002, r=0.842). In vitro, stimulation with VEGF induced the expression of vasohibin-1 mRNA in RASFs under normoxic conditions, and stimulation with cytokines induced vasohibin-1 mRNA expression under a hypoxic condition. These results suggest that vasohibin-1 was expressed in RA synovial tissue and might be regulated by inflammatory cytokines." @default.
• W1583083639 created "2016-06-24" @default.
• W1583083639 creator A5017605422 @default.
• W1583083639 creator A5018983045 @default.
• W1583083639 creator A5023752487 @default.
• W1583083639 creator A5035617971 @default.
• W1583083639 creator A5039655833 @default.
• W1583083639 creator A5045885604 @default.
• W1583083639 creator A5050198503 @default.
• W1583083639 creator A5073398055 @default.
• W1583083639 creator A5075264923 @default.
• W1583083639 creator A5081462168 @default.
• W1583083639 creator A5087761019 @default.
• W1583083639 date "2009-12-01" @default.
• W1583083639 modified "2023-09-26" @default.
• W1583083639 title "Inflammatory cytokine-induced expression of vasohibin-1 by rheumatoid synovial fibroblasts." @default.
• W1583083639 doi "https://doi.org/10.18926/amo/31820" @default.
• W1583083639 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20035291" @default.
• W1583083639 hasPublicationYear "2009" @default.
• W1583083639 type Work @default.
• W1583083639 sameAs 1583083639 @default.
• W1583083639 citedByCount "9" @default.
• W1583083639 countsByYear W15830836392013 @default.
• W1583083639 countsByYear W15830836392014 @default.
• W1583083639 countsByYear W15830836392017 @default.
• W1583083639 countsByYear W15830836392018 @default.
• W1583083639 crossrefType "journal-article" @default.
• W1583083639 hasAuthorship W1583083639A5017605422 @default.
• W1583083639 hasAuthorship W1583083639A5018983045 @default.
• W1583083639 hasAuthorship W1583083639A5023752487 @default.
• W1583083639 hasAuthorship W1583083639A5035617971 @default.
• W1583083639 hasAuthorship W1583083639A5039655833 @default.
• W1583083639 hasAuthorship W1583083639A5045885604 @default.
• W1583083639 hasAuthorship W1583083639A5050198503 @default.
• W1583083639 hasAuthorship W1583083639A5073398055 @default.
• W1583083639 hasAuthorship W1583083639A5075264923 @default.
• W1583083639 hasAuthorship W1583083639A5081462168 @default.
• W1583083639 hasAuthorship W1583083639A5087761019 @default.
• W1583083639 hasConcept C142724271 @default.
• W1583083639 hasConcept C164027704 @default.
• W1583083639 hasConcept C167734588 @default.
• W1583083639 hasConcept C185592680 @default.
• W1583083639 hasConcept C203014093 @default.
• W1583083639 hasConcept C204232928 @default.
• W1583083639 hasConcept C204787440 @default.
• W1583083639 hasConcept C2776164576 @default.
• W1583083639 hasConcept C2776914184 @default.
• W1583083639 hasConcept C2777025900 @default.
• W1583083639 hasConcept C2777077863 @default.
• W1583083639 hasConcept C2777575956 @default.
• W1583083639 hasConcept C2777652487 @default.
• W1583083639 hasConcept C2778690821 @default.
• W1583083639 hasConcept C2780394083 @default.
• W1583083639 hasConcept C502942594 @default.
• W1583083639 hasConcept C71924100 @default.
• W1583083639 hasConceptScore W1583083639C142724271 @default.
• W1583083639 hasConceptScore W1583083639C164027704 @default.
• W1583083639 hasConceptScore W1583083639C167734588 @default.
• W1583083639 hasConceptScore W1583083639C185592680 @default.
• W1583083639 hasConceptScore W1583083639C203014093 @default.
• W1583083639 hasConceptScore W1583083639C204232928 @default.
• W1583083639 hasConceptScore W1583083639C204787440 @default.
• W1583083639 hasConceptScore W1583083639C2776164576 @default.
• W1583083639 hasConceptScore W1583083639C2776914184 @default.
• W1583083639 hasConceptScore W1583083639C2777025900 @default.
• W1583083639 hasConceptScore W1583083639C2777077863 @default.
• W1583083639 hasConceptScore W1583083639C2777575956 @default.
• W1583083639 hasConceptScore W1583083639C2777652487 @default.
• W1583083639 hasConceptScore W1583083639C2778690821 @default.
• W1583083639 hasConceptScore W1583083639C2780394083 @default.
• W1583083639 hasConceptScore W1583083639C502942594 @default.
• W1583083639 hasConceptScore W1583083639C71924100 @default.
• W1583083639 hasIssue "6" @default.
• W1583083639 hasLocation W15830836391 @default.
• W1583083639 hasOpenAccess W1583083639 @default.
• W1583083639 hasPrimaryLocation W15830836391 @default.
• W1583083639 hasRelatedWork W1980079044 @default.
• W1583083639 hasRelatedWork W1980829795 @default.
• W1583083639 hasRelatedWork W1983556635 @default.
• W1583083639 hasRelatedWork W1999667558 @default.
• W1583083639 hasRelatedWork W2001587448 @default.
• W1583083639 hasRelatedWork W2022810274 @default.
• W1583083639 hasRelatedWork W2033682302 @default.
• W1583083639 hasRelatedWork W2074779122 @default.
• W1583083639 hasRelatedWork W2084464937 @default.
• W1583083639 hasRelatedWork W2095518272 @default.
• W1583083639 hasRelatedWork W2096826728 @default.
• W1583083639 hasRelatedWork W2120927517 @default.
• W1583083639 hasRelatedWork W2127681935 @default.
• W1583083639 hasRelatedWork W2131798870 @default.
• W1583083639 hasRelatedWork W2135962444 @default.
• W1583083639 hasRelatedWork W2136455486 @default.
• W1583083639 hasRelatedWork W2137061409 @default.
• W1583083639 hasRelatedWork W2155580025 @default.
• W1583083639 hasRelatedWork W2159304803 @default.
• W1583083639 hasRelatedWork W2303368769 @default.
• W1583083639 hasVolume "63" @default.
• W1583083639 isParatext "false" @default.

• next