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• W1583207878 abstract "Thio-based “click” chemistry approaches to synthesizing sulfur-containing functionalized sugar molecules are compiled and reviewed. Among multiple strategies for incorporation of sulfur into desirable thio-link for further functionalization, two methods are clearly emerging from the available pool of tools, specifically, thiol-ene coupling and thiol Michael enone addition. Both approaches are highly stereoselective and form adducts in the overall high yield. The starting templates for both thio-click reactions are fully protected thiols. Their nucleophilicity is sufficient enough to produce the coupling products in at least moderate yields." @default.
• W1583207878 created "2016-06-24" @default.
• W1583207878 creator A5011422263 @default.
• W1583207878 date "2013-02-06" @default.
• W1583207878 modified "2023-09-23" @default.
• W1583207878 title "Thio-Click Chemistry in Glycoscience: Overview and Perspectives" @default.
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• W1583207878 doi "https://doi.org/10.1002/9781118526996.ch2" @default.
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