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• W1583760877 abstract "The focus of this Editorial is recent developments in magnetic resonance imaging (MRI) modalities for evaluation of the microstructure and macromolecular organisation of articular cartilage. We place a specific emphasis on three types of measurements: (1) MRI transverse spin-relaxation mapping (T2 mapping); (2) diffusion-tensor imaging; and (3) compression micro-MRI (uMRI) measurements of articular cartilage in vitro. Such studies have a significant role to play in improving the understanding of the fundamental biomechanics of articular cartilage and in the development of in vitro models of early osteoarthritis. We discuss how the supramolecular organisation of the cartilage extracellular matrix and its behaviour under mechanical compression can be inferred from diffusion-tensor and T2 maps with in-plane resolution ~100 um. The emphasis is on in vitro studies performed under controlled physiological conditions but in vivo applications of T2 mapping and DTI are also briefly discussed." @default.
• W1583760877 created "2016-06-24" @default.
• W1583760877 creator A5045056924 @default.
• W1583760877 date "2012-01-01" @default.
• W1583760877 modified "2023-09-26" @default.
• W1583760877 title "Microstructural magnetic resonance imaging of articular cartilage" @default.
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• W1583760877 doi "https://doi.org/10.3233/bsi-2012-0003" @default.
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