FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1584532694> ?p ?o ?g. }

• W1584532694 endingPage "1708" @default.
• W1584532694 startingPage "1700" @default.
• W1584532694 abstract "Acute lymphoblastic leukemia (ALL) is the most common cancer of childhood. Some evidence suggests differences in clinical and cytogenetic characteristics of ALL based on geographic and ethnic variations. However, data on ALL characteristics and early outcome of therapy from low/middle-income countries such as Pakistan are scanty.A prospective, multi-institutional cohort study in Karachi enrolled 646 newly diagnosed children with ALL over 3 years. Standard forms were used to collect demographic, clinical, and laboratory data at presentation and at the end of induction.Of the total, 66.1% (n = 427) were males. Median age was 6 (mean ± SE 6.87 ± 0.16; range 0.16-18) years. The most common clinical presentation was fever (88.7%). BPC-ALL was diagnosed in 78.5%, while 17.5% had T-ALL; 28.8% had a WBC >50 × 10(9) /L. With 316 patients karyotyped, hypodiploidy and hyperdiploidy were seen in 5.1% and 10.7%, respectively. Of those tested, ETV6-RUNX1 translocation was detected in 13.2%, while BCR-ABL1 translocation and MLL gene rearrangements were seen in 7.3% and 4.6%, respectively. The cumulative loss to follow up before and during induction was 12.8% (n = 83) and 11.5% (n = 74) died before or during this phase. Induction was successfully completed by only 75.6% (n = 489) of the entire cohort and 69.6% (n = 450) achieved remission.These patients had ALL with higher risk features than that reported from developed countries. One quarter failed to complete induction chemotherapy. This suboptimal result requires further study and development of innovative interventions, particularly focusing on the causes and solutions for late referral, abandonment, and infections." @default.
• W1584532694 created "2016-06-24" @default.
• W1584532694 creator A5002673326 @default.
• W1584532694 creator A5013702367 @default.
• W1584532694 creator A5035931636 @default.
• W1584532694 creator A5044301352 @default.
• W1584532694 creator A5059411454 @default.
• W1584532694 creator A5074239144 @default.
• W1584532694 creator A5080396108 @default.
• W1584532694 creator A5083607303 @default.
• W1584532694 creator A5090564291 @default.
• W1584532694 date "2015-05-15" @default.
• W1584532694 modified "2023-10-10" @default.
• W1584532694 title "Clinical features and induction outcome of childhood acute lymphoblastic leukemia in a lower/middle income population: A multi-institutional report from Pakistan" @default.
• W1584532694 cites W1644813534 @default.
• W1584532694 cites W1968622258 @default.
• W1584532694 cites W1968903652 @default.
• W1584532694 cites W1980028072 @default.
• W1584532694 cites W2004100998 @default.
• W1584532694 cites W2004450889 @default.
• W1584532694 cites W2007437787 @default.
• W1584532694 cites W2015570395 @default.
• W1584532694 cites W2021349012 @default.
• W1584532694 cites W2044031908 @default.
• W1584532694 cites W2047782233 @default.
• W1584532694 cites W2047893957 @default.
• W1584532694 cites W2064441042 @default.
• W1584532694 cites W2113030986 @default.
• W1584532694 cites W2119685895 @default.
• W1584532694 cites W2126727049 @default.
• W1584532694 cites W2146473098 @default.
• W1584532694 cites W2151350992 @default.
• W1584532694 cites W2163465401 @default.
• W1584532694 cites W2164358985 @default.
• W1584532694 cites W2168902671 @default.
• W1584532694 cites W2336990540 @default.
• W1584532694 cites W2440705721 @default.
• W1584532694 cites W4239897690 @default.
• W1584532694 doi "https://doi.org/10.1002/pbc.25583" @default.
• W1584532694 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25982135" @default.
• W1584532694 hasPublicationYear "2015" @default.
• W1584532694 type Work @default.
• W1584532694 sameAs 1584532694 @default.
• W1584532694 citedByCount "20" @default.
• W1584532694 countsByYear W15845326942016 @default.
• W1584532694 countsByYear W15845326942017 @default.
• W1584532694 countsByYear W15845326942019 @default.
• W1584532694 countsByYear W15845326942020 @default.
• W1584532694 countsByYear W15845326942021 @default.
• W1584532694 countsByYear W15845326942022 @default.
• W1584532694 countsByYear W15845326942023 @default.
• W1584532694 crossrefType "journal-article" @default.
• W1584532694 hasAuthorship W1584532694A5002673326 @default.
• W1584532694 hasAuthorship W1584532694A5013702367 @default.
• W1584532694 hasAuthorship W1584532694A5035931636 @default.
• W1584532694 hasAuthorship W1584532694A5044301352 @default.
• W1584532694 hasAuthorship W1584532694A5059411454 @default.
• W1584532694 hasAuthorship W1584532694A5074239144 @default.
• W1584532694 hasAuthorship W1584532694A5080396108 @default.
• W1584532694 hasAuthorship W1584532694A5083607303 @default.
• W1584532694 hasAuthorship W1584532694A5090564291 @default.
• W1584532694 hasBestOaLocation W15845326941 @default.
• W1584532694 hasConcept C126322002 @default.
• W1584532694 hasConcept C187212893 @default.
• W1584532694 hasConcept C188816634 @default.
• W1584532694 hasConcept C2776611710 @default.
• W1584532694 hasConcept C2776694085 @default.
• W1584532694 hasConcept C2908647359 @default.
• W1584532694 hasConcept C71924100 @default.
• W1584532694 hasConcept C72563966 @default.
• W1584532694 hasConcept C99454951 @default.
• W1584532694 hasConceptScore W1584532694C126322002 @default.
• W1584532694 hasConceptScore W1584532694C187212893 @default.
• W1584532694 hasConceptScore W1584532694C188816634 @default.
• W1584532694 hasConceptScore W1584532694C2776611710 @default.
• W1584532694 hasConceptScore W1584532694C2776694085 @default.
• W1584532694 hasConceptScore W1584532694C2908647359 @default.
• W1584532694 hasConceptScore W1584532694C71924100 @default.
• W1584532694 hasConceptScore W1584532694C72563966 @default.
• W1584532694 hasConceptScore W1584532694C99454951 @default.
• W1584532694 hasFunder F4320309930 @default.
• W1584532694 hasIssue "10" @default.
• W1584532694 hasLocation W15845326941 @default.
• W1584532694 hasLocation W15845326942 @default.
• W1584532694 hasOpenAccess W1584532694 @default.
• W1584532694 hasPrimaryLocation W15845326941 @default.
• W1584532694 hasRelatedWork W2071535500 @default.
• W1584532694 hasRelatedWork W2315085516 @default.
• W1584532694 hasRelatedWork W2371666691 @default.
• W1584532694 hasRelatedWork W2378355431 @default.
• W1584532694 hasRelatedWork W2412545272 @default.
• W1584532694 hasRelatedWork W2568490671 @default.
• W1584532694 hasRelatedWork W2603773853 @default.
• W1584532694 hasRelatedWork W2782785108 @default.
• W1584532694 hasRelatedWork W2952239533 @default.
• W1584532694 hasRelatedWork W3081622774 @default.
• W1584532694 hasVolume "62" @default.
• W1584532694 isParatext "false" @default.

• next