Matches in SemOpenAlex for { <https://semopenalex.org/work/W1584584037> ?p ?o ?g. }
- W1584584037 endingPage "735" @default.
- W1584584037 startingPage "731" @default.
- W1584584037 abstract "Abstract Viruses are commonly used for the delivery of genes coding for tumor-associated Ags to elicit tumor-specific immune responses. The success of viral vectors has been limited in preclinical and clinical trials in part because of antiviral immunity. We investigated the ability of a collagen-based matrix (Gelfoam; Pharmacia and Upjohn, Kalamazoo, MI) to improve CTL activation by recombinant adenovirus. The data show that coinjection of Gelfoam with type 5 adenovirus recombinant for prostate-specific Ag (Ad5-PSA) enhanced CTL activation. Ad5-PSA priming in Gelfoam also abrogated the inhibitory effects of adenoviral immunity on CTL activation in mice naive to PSA but immune to adenovirus. Finally, Gelfoam enhanced immunization in a self-Ag model using type 5 adenovirus recombinant for membrane-bound OVA (Ad5-mOVA) in rat insulin promoter (RIP)-mOVA-transgenic mice. Thus, Gelfoam enhances CTL activation by recombinant viral vectors in a setting where preformed Ab to the virus is present and also in a tolerant self-Ag model." @default.
- W1584584037 created "2016-06-24" @default.
- W1584584037 creator A5001791370 @default.
- W1584584037 creator A5027600557 @default.
- W1584584037 creator A5032781343 @default.
- W1584584037 creator A5067229838 @default.
- W1584584037 creator A5081030515 @default.
- W1584584037 creator A5088442918 @default.
- W1584584037 creator A5088484021 @default.
- W1584584037 date "2001-01-15" @default.
- W1584584037 modified "2023-09-27" @default.
- W1584584037 title "Cutting Edge: Restoration of the Ability to Generate CTL in Mice Immune to Adenovirus by Delivery of Virus in a Collagen-Based Matrix" @default.
- W1584584037 cites W1535342352 @default.
- W1584584037 cites W1554669092 @default.
- W1584584037 cites W1589374329 @default.
- W1584584037 cites W1663973802 @default.
- W1584584037 cites W1967228746 @default.
- W1584584037 cites W1977298268 @default.
- W1584584037 cites W1981448223 @default.
- W1584584037 cites W2008980266 @default.
- W1584584037 cites W2020457329 @default.
- W1584584037 cites W2024164896 @default.
- W1584584037 cites W2026470830 @default.
- W1584584037 cites W2046214793 @default.
- W1584584037 cites W2050474055 @default.
- W1584584037 cites W2056479362 @default.
- W1584584037 cites W2064744205 @default.
- W1584584037 cites W2065381303 @default.
- W1584584037 cites W2067965474 @default.
- W1584584037 cites W2074773332 @default.
- W1584584037 cites W2075632202 @default.
- W1584584037 cites W2078321284 @default.
- W1584584037 cites W2089559330 @default.
- W1584584037 cites W2101340942 @default.
- W1584584037 cites W2116445116 @default.
- W1584584037 cites W2122957377 @default.
- W1584584037 cites W2131095976 @default.
- W1584584037 cites W2138913424 @default.
- W1584584037 cites W2142066580 @default.
- W1584584037 cites W2143063298 @default.
- W1584584037 cites W2147103876 @default.
- W1584584037 cites W2151902657 @default.
- W1584584037 cites W2152899663 @default.
- W1584584037 cites W2157992421 @default.
- W1584584037 cites W2166676682 @default.
- W1584584037 cites W2412045520 @default.
- W1584584037 cites W3021254998 @default.
- W1584584037 cites W4313332005 @default.
- W1584584037 doi "https://doi.org/10.4049/jimmunol.166.2.731" @default.
- W1584584037 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11145643" @default.
- W1584584037 hasPublicationYear "2001" @default.
- W1584584037 type Work @default.
- W1584584037 sameAs 1584584037 @default.
- W1584584037 citedByCount "54" @default.
- W1584584037 countsByYear W15845840372012 @default.
- W1584584037 countsByYear W15845840372013 @default.
- W1584584037 countsByYear W15845840372014 @default.
- W1584584037 countsByYear W15845840372015 @default.
- W1584584037 countsByYear W15845840372017 @default.
- W1584584037 countsByYear W15845840372018 @default.
- W1584584037 countsByYear W15845840372019 @default.
- W1584584037 countsByYear W15845840372020 @default.
- W1584584037 countsByYear W15845840372021 @default.
- W1584584037 countsByYear W15845840372022 @default.
- W1584584037 countsByYear W15845840372023 @default.
- W1584584037 crossrefType "journal-article" @default.
- W1584584037 hasAuthorship W1584584037A5001791370 @default.
- W1584584037 hasAuthorship W1584584037A5027600557 @default.
- W1584584037 hasAuthorship W1584584037A5032781343 @default.
- W1584584037 hasAuthorship W1584584037A5067229838 @default.
- W1584584037 hasAuthorship W1584584037A5081030515 @default.
- W1584584037 hasAuthorship W1584584037A5088442918 @default.
- W1584584037 hasAuthorship W1584584037A5088484021 @default.
- W1584584037 hasBestOaLocation W15845840371 @default.
- W1584584037 hasConcept C100701293 @default.
- W1584584037 hasConcept C102230213 @default.
- W1584584037 hasConcept C104317684 @default.
- W1584584037 hasConcept C147969180 @default.
- W1584584037 hasConcept C159047783 @default.
- W1584584037 hasConcept C167672396 @default.
- W1584584037 hasConcept C203014093 @default.
- W1584584037 hasConcept C2522874641 @default.
- W1584584037 hasConcept C2776954459 @default.
- W1584584037 hasConcept C32470452 @default.
- W1584584037 hasConcept C39060996 @default.
- W1584584037 hasConcept C40767141 @default.
- W1584584037 hasConcept C55493867 @default.
- W1584584037 hasConcept C59822182 @default.
- W1584584037 hasConcept C81444415 @default.
- W1584584037 hasConcept C86803240 @default.
- W1584584037 hasConcept C8891405 @default.
- W1584584037 hasConceptScore W1584584037C100701293 @default.
- W1584584037 hasConceptScore W1584584037C102230213 @default.
- W1584584037 hasConceptScore W1584584037C104317684 @default.
- W1584584037 hasConceptScore W1584584037C147969180 @default.
- W1584584037 hasConceptScore W1584584037C159047783 @default.
- W1584584037 hasConceptScore W1584584037C167672396 @default.
- W1584584037 hasConceptScore W1584584037C203014093 @default.