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- W1585074713 abstract "Programmed cell death occurs physiologically via distinct morphological and biochemical features, namely apoptosis, necroptosis, or programmed necrosis. In all these processes, caspases play a crucial role. These cysteinyl aspartate-specific proteases (hence the name caspases) include a dozen of distinct enzymes that are involved in inflammation, activation, or execution of the apoptotic biochemical events. Here, we briefly outline the biochemical events involving capspases in cell death, with its clinical implication. The involvement in several oncological, infective and neurological diseases, as well as the development of low molecular compounds provide interesting therapeutic perspective in this growing area of research." @default.
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- W1585074713 date "2009-12-15" @default.
- W1585074713 modified "2023-10-07" @default.
- W1585074713 title "Caspases and Cell Death" @default.
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- W1585074713 doi "https://doi.org/10.1002/9780470015902.a0021562" @default.
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