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- W1585364102 abstract "Publisher Summary Working memory (WM) is the system that allows for the short-term storage and processing of information and is essential for the performance of complex cognitive processes. This chapter uses both high- and low-frequency repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex (DLPFC) to disrupt 3-back task performance. Conceptually, rTMS introduces “random noise” into the organized neuronal functioning during a given behavior, where the pattern of activity occurring at the time of stimulation is disrupted but the mechanisms by which high- and low-frequency stimulation act is unclear. It is believed that an effect of TMS was not seen on a demanding WM task due to the many factors involved in rTMS itself and the nature of the WM network, acting together. It is possible that the brain region stimulated is not essential in the performance of a WM task such as the 3-back task. The optimal parameters of rTMS, however, that are required to produce a significant “virtual lesion” are unclear and one highlights the importance of stimulus intensity and frequency, coil placement and pulse timing in any experiment." @default.
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- W1585364102 date "2003-01-01" @default.
- W1585364102 modified "2023-10-18" @default.
- W1585364102 title "Chapter 18 Disruption of the neural correlates of working memory using high- and low-frequency repetitive transcranial magnetic stimulation: a negative study" @default.
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- W1585364102 doi "https://doi.org/10.1016/s1567-424x(09)70221-1" @default.
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