Matches in SemOpenAlex for { <https://semopenalex.org/work/W1586037269> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W1586037269 endingPage "153" @default.
- W1586037269 startingPage "149" @default.
- W1586037269 abstract "Most of patients suffering from HLA class I deficiency due to mutations in TAP genes show a significative increase of the peripheral minor Vdelta1+ subpopulation of gammadelta T cells. Surface expression of inhibitory receptors (IR) for HLA class I molecules have been mainly attributed to Vdelta2+ gammadelta T clones. In this study we have analysed the expression of these receptors in both subsets of gammadelta T peripheral lymphocytes. We studied 16 healthy controls and a reported case of homozygous TAP2 mutation with a marked increase of Vdelta1+ gammadelta T cells. MICA/B presence in monocytes was also evaluated. In healthy subjects, the expression of CD94 and CD94/NKG2A was higher in the Vdelta2+ subset but cells bearing the IR ILT2 were found increased in the Vdelta1+. The patient Vdelta2+ gammadelta T cells showed the same IR expression than normal controls, in contrast the Vdelta1+ subset presented a special pattern of very high expression of CD94 and ILT2 and low of CD94/NKG2A. The presence of a new IR poorly represented in healthy individuals could account for the selective increase of Vdelta1+ gammadelta T in TAP-deficient patients. MICA/B surface expression in monocytes was not shifted in our patient." @default.
- W1586037269 created "2016-06-24" @default.
- W1586037269 creator A5015536037 @default.
- W1586037269 creator A5020186205 @default.
- W1586037269 creator A5058215131 @default.
- W1586037269 creator A5067390539 @default.
- W1586037269 creator A5083916876 @default.
- W1586037269 creator A5090658025 @default.
- W1586037269 date "2003-04-03" @default.
- W1586037269 modified "2023-10-16" @default.
- W1586037269 title "Skewed inhibitory receptors expression in a TAP2-deficient patient" @default.
- W1586037269 cites W1542899523 @default.
- W1586037269 cites W1573613966 @default.
- W1586037269 cites W1642772401 @default.
- W1586037269 cites W1976510602 @default.
- W1586037269 cites W2019201865 @default.
- W1586037269 cites W2056204715 @default.
- W1586037269 cites W2089484373 @default.
- W1586037269 cites W2094662815 @default.
- W1586037269 cites W2095569760 @default.
- W1586037269 cites W2119333066 @default.
- W1586037269 cites W2131596029 @default.
- W1586037269 cites W2139686340 @default.
- W1586037269 cites W2154399041 @default.
- W1586037269 doi "https://doi.org/10.1016/s0165-2478(03)00005-1" @default.
- W1586037269 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12644316" @default.
- W1586037269 hasPublicationYear "2003" @default.
- W1586037269 type Work @default.
- W1586037269 sameAs 1586037269 @default.
- W1586037269 citedByCount "4" @default.
- W1586037269 countsByYear W15860372692022 @default.
- W1586037269 countsByYear W15860372692023 @default.
- W1586037269 crossrefType "journal-article" @default.
- W1586037269 hasAuthorship W1586037269A5015536037 @default.
- W1586037269 hasAuthorship W1586037269A5020186205 @default.
- W1586037269 hasAuthorship W1586037269A5058215131 @default.
- W1586037269 hasAuthorship W1586037269A5067390539 @default.
- W1586037269 hasAuthorship W1586037269A5083916876 @default.
- W1586037269 hasAuthorship W1586037269A5090658025 @default.
- W1586037269 hasConcept C147483822 @default.
- W1586037269 hasConcept C153911025 @default.
- W1586037269 hasConcept C170493617 @default.
- W1586037269 hasConcept C188280979 @default.
- W1586037269 hasConcept C203014093 @default.
- W1586037269 hasConcept C2992881475 @default.
- W1586037269 hasConcept C54355233 @default.
- W1586037269 hasConcept C86803240 @default.
- W1586037269 hasConceptScore W1586037269C147483822 @default.
- W1586037269 hasConceptScore W1586037269C153911025 @default.
- W1586037269 hasConceptScore W1586037269C170493617 @default.
- W1586037269 hasConceptScore W1586037269C188280979 @default.
- W1586037269 hasConceptScore W1586037269C203014093 @default.
- W1586037269 hasConceptScore W1586037269C2992881475 @default.
- W1586037269 hasConceptScore W1586037269C54355233 @default.
- W1586037269 hasConceptScore W1586037269C86803240 @default.
- W1586037269 hasIssue "2" @default.
- W1586037269 hasLocation W15860372691 @default.
- W1586037269 hasLocation W15860372692 @default.
- W1586037269 hasOpenAccess W1586037269 @default.
- W1586037269 hasPrimaryLocation W15860372691 @default.
- W1586037269 hasRelatedWork W1513096311 @default.
- W1586037269 hasRelatedWork W1965116372 @default.
- W1586037269 hasRelatedWork W1987713980 @default.
- W1586037269 hasRelatedWork W2008949385 @default.
- W1586037269 hasRelatedWork W2053502407 @default.
- W1586037269 hasRelatedWork W2062101683 @default.
- W1586037269 hasRelatedWork W2220102944 @default.
- W1586037269 hasRelatedWork W2414745257 @default.
- W1586037269 hasRelatedWork W2417789235 @default.
- W1586037269 hasRelatedWork W2480763126 @default.
- W1586037269 hasVolume "86" @default.
- W1586037269 isParatext "false" @default.
- W1586037269 isRetracted "false" @default.
- W1586037269 magId "1586037269" @default.
- W1586037269 workType "article" @default.