FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1586270996> ?p ?o ?g. }

• W1586270996 endingPage "147" @default.
• W1586270996 startingPage "141" @default.
• W1586270996 abstract "Several studies support a genetic influence on obsessive-compulsive disorder (OCD) etiology. The role of glutamate as an important neurotransmitter affecting OCD pathophysiology has been supported by neuroimaging, animal model, medication, and initial candidate gene studies. Genes involved in glutamatergic pathways, such as the glutamate receptor, ionotropic, kainate 2 (GRIK2), have been associated with OCD in previous studies. This study examines GRIK2 as a candidate gene for OCD susceptibility in a family-based approach. Probands had full DSM-IV diagnostic criteria for OCD. Forty-seven OCD probands and their parents were recruited from tertiary care OCD specialty clinics from France and USA. Genotypes of single nucleotide polymorphism (SNP) markers and related haplotypes were analyzed using Haploview and FBAT software. The polymorphism at rs1556995 (P= 0.0027; permuted P-value = 0.03) was significantly associated with the presence of OCD. Also, the two marker haplotype rs1556995/rs1417182, was significantly associated with OCD (P= 0.0019, permuted P-value = 0.01). This study supports previously reported findings of association between proximal GRIK2 SNPs and OCD in a comprehensive evaluation of the gene. Further study with independent samples and larger sample sizes is required." @default.
• W1586270996 created "2016-06-24" @default.
• W1586270996 creator A5017405820 @default.
• W1586270996 creator A5020448299 @default.
• W1586270996 creator A5023240794 @default.
• W1586270996 creator A5032139668 @default.
• W1586270996 creator A5032615209 @default.
• W1586270996 creator A5038038028 @default.
• W1586270996 creator A5043863759 @default.
• W1586270996 date "2010-03-29" @default.
• W1586270996 modified "2023-10-17" @default.
• W1586270996 title "Association Between Polymorphisms in GRIK2 Gene and Obsessive-Compulsive Disorder: A Family-Based Study" @default.
• W1586270996 cites W1971926009 @default.
• W1586270996 cites W1973748621 @default.
• W1586270996 cites W1979292526 @default.
• W1586270996 cites W1983302342 @default.
• W1586270996 cites W1984518477 @default.
• W1586270996 cites W1988536772 @default.
• W1586270996 cites W1992922886 @default.
• W1586270996 cites W1998622616 @default.
• W1586270996 cites W2000611522 @default.
• W1586270996 cites W2002375162 @default.
• W1586270996 cites W2010270082 @default.
• W1586270996 cites W2017032137 @default.
• W1586270996 cites W2034593916 @default.
• W1586270996 cites W2048695562 @default.
• W1586270996 cites W2053626793 @default.
• W1586270996 cites W2058108929 @default.
• W1586270996 cites W2061593669 @default.
• W1586270996 cites W2063473805 @default.
• W1586270996 cites W2077846197 @default.
• W1586270996 cites W2080914771 @default.
• W1586270996 cites W2082145187 @default.
• W1586270996 cites W2090123666 @default.
• W1586270996 cites W2097386588 @default.
• W1586270996 cites W2105697752 @default.
• W1586270996 cites W2111396411 @default.
• W1586270996 cites W2116655758 @default.
• W1586270996 cites W2118738821 @default.
• W1586270996 cites W2126718294 @default.
• W1586270996 cites W2142016029 @default.
• W1586270996 cites W2143027421 @default.
• W1586270996 cites W2155635136 @default.
• W1586270996 cites W2162530578 @default.
• W1586270996 cites W2164124971 @default.
• W1586270996 cites W2168681133 @default.
• W1586270996 cites W2169105392 @default.
• W1586270996 cites W4211038581 @default.
• W1586270996 doi "https://doi.org/10.1111/j.1755-5949.2009.00130.x" @default.
• W1586270996 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6493828" @default.
• W1586270996 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20370803" @default.
• W1586270996 hasPublicationYear "2010" @default.
• W1586270996 type Work @default.
• W1586270996 sameAs 1586270996 @default.
• W1586270996 citedByCount "44" @default.
• W1586270996 countsByYear W15862709962012 @default.
• W1586270996 countsByYear W15862709962013 @default.
• W1586270996 countsByYear W15862709962014 @default.
• W1586270996 countsByYear W15862709962015 @default.
• W1586270996 countsByYear W15862709962016 @default.
• W1586270996 countsByYear W15862709962017 @default.
• W1586270996 countsByYear W15862709962018 @default.
• W1586270996 countsByYear W15862709962019 @default.
• W1586270996 countsByYear W15862709962020 @default.
• W1586270996 countsByYear W15862709962021 @default.
• W1586270996 countsByYear W15862709962022 @default.
• W1586270996 crossrefType "journal-article" @default.
• W1586270996 hasAuthorship W1586270996A5017405820 @default.
• W1586270996 hasAuthorship W1586270996A5020448299 @default.
• W1586270996 hasAuthorship W1586270996A5023240794 @default.
• W1586270996 hasAuthorship W1586270996A5032139668 @default.
• W1586270996 hasAuthorship W1586270996A5032615209 @default.
• W1586270996 hasAuthorship W1586270996A5038038028 @default.
• W1586270996 hasAuthorship W1586270996A5043863759 @default.
• W1586270996 hasBestOaLocation W15862709961 @default.
• W1586270996 hasConcept C104317684 @default.
• W1586270996 hasConcept C118552586 @default.
• W1586270996 hasConcept C135763542 @default.
• W1586270996 hasConcept C139275648 @default.
• W1586270996 hasConcept C153209595 @default.
• W1586270996 hasConcept C197754878 @default.
• W1586270996 hasConcept C54355233 @default.
• W1586270996 hasConcept C60644358 @default.
• W1586270996 hasConcept C69991583 @default.
• W1586270996 hasConcept C71924100 @default.
• W1586270996 hasConcept C86803240 @default.
• W1586270996 hasConceptScore W1586270996C104317684 @default.
• W1586270996 hasConceptScore W1586270996C118552586 @default.
• W1586270996 hasConceptScore W1586270996C135763542 @default.
• W1586270996 hasConceptScore W1586270996C139275648 @default.
• W1586270996 hasConceptScore W1586270996C153209595 @default.
• W1586270996 hasConceptScore W1586270996C197754878 @default.
• W1586270996 hasConceptScore W1586270996C54355233 @default.
• W1586270996 hasConceptScore W1586270996C60644358 @default.
• W1586270996 hasConceptScore W1586270996C69991583 @default.
• W1586270996 hasConceptScore W1586270996C71924100 @default.
• W1586270996 hasConceptScore W1586270996C86803240 @default.
• W1586270996 hasIssue "3" @default.

• next