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- W1586321785 abstract "The Wnt signaling pathway is involved in the development and progression of many human cancers, yet attempts to target the pathway therapeutically have been disappointing to date. The recent discovery that the ROR2 receptor tyrosine kinase (RTK) is a novel Wnt receptor provides the potential to target the non-canonical Wnt pathway for cancer treatments. As a member of the RTK superfamily of surface receptors ROR2 appears to possess dual roles as a tumor suppressor or activator depending on tumor type. This review will explore the dual role of ROR2 in tumorigenesis and provide an up to date analysis of current literature in this rapidly expanding field." @default.
- W1586321785 created "2016-06-24" @default.
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- W1586321785 date "2013-01-10" @default.
- W1586321785 modified "2023-10-10" @default.
- W1586321785 title "The dual role of the novel Wnt receptor tyrosine kinase, ROR2, in human carcinogenesis" @default.
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- W1586321785 doi "https://doi.org/10.1002/ijc.27984" @default.
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