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• W1586709208 abstract "Objectives: Aging is a natural process involving many aspects and including virtually every organ and tissue. Kidney is usually regarded as an important part during the overall process of aging. We aimed at investigating the aging trend of renal function in elderly community dwellers in Taiwan through a practical approach of renal function estimation. Methods: Data were derived from the latest Nutrition and Health Survey in Taiwan (NAHSIT) for the elderly, conducted from 1999 to 2000 with a complex sampling scheme to obtain representative samples from general communities in Taiwan. Ultimately, after the exclusion of those with morbid conditions likely to influence renal function, 508 target samples (265 males and 243 females) had been recruited from a total of 2,064 subjects aged 65 years and over (1,047 males and 1,017 females) as the target sample subjects. Practical approach of the transition of renal function estimation (eC(subscript Cr)) was carried out by using Cockcroft and Gault formula from serum creatinine level, age and body weight. And the results had been examined with Trend test, Logrank test, and necessary regression analyses. Results: The results showed that eC(subscript Cr) for the total samples read 65.5±15, 57.0±15, 51.0±12 & 39.6±15 ml/min respectively in the age strata of 65-69, 70-74, 75-79 and 80+ in male, and 63.0±15, 58.5±13, 52.2±12 & 39.8±10 ml/min respectively in each age strata of the healthier male subjects recruited. eC(subscript Cr), on the other hand, emerged as 61.6±14, 54.1±25, 45.3±14 & 37.3±10 ml/min and 59.1±12, 52.8±13, 47.5±18 & 35.5±11 ml/min respectively in the female counterparts. There showed a trend of transitional decay of renal function by age in the total sample group and in the healthier recruited sample group; the trend, however, was not significant statistically. Moreover, there was no significant difference between total-sample approach and the healthier-sample approach. Some anthropometric factors and health-related behaviors might play their roles. Conclusions: This study offered some evidence-based outcomes for probing into the natural decay of kidney function, and even the quasi-or semi-norm renal function in the elderly, which can be regarded as an important indicator of clinical, research, public health, health education and even policy making in Taiwan. Certainly, for a more valid and precise estimation, further advanced longitudinal study design is still necessary." @default.
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• W1586709208 date "2006-02-01" @default.
• W1586709208 modified "2023-09-23" @default.
• W1586709208 title "Aging of Renal Function Estimation in Elderly Community Dwellers Experiences in Taiwanese Population" @default.
• W1586709208 doi "https://doi.org/10.29462/tgg.200602.0003" @default.
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