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- W1586984916 abstract "The labelling of cellular targets with fluorescent probes is used widely in live cell imaging to identify and monitor intracellular events. Excitation of probes with light, however, can result in phototoxicity and photobleaching – factors that can seriously compromise fluorescence time-lapse recordings especially in confocal microscopy. Laser-induced phototoxicity and photobleaching can be reduced with an innovative technology known as ‘Controlled Light Exposure Microscopy (CLEM)’. Here, photobleaching and cell survival are compared when imaged with a Nikon C1 confocal system configured with, and without, CLEM." @default.
- W1586984916 created "2016-06-24" @default.
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- W1586984916 date "2007-11-01" @default.
- W1586984916 modified "2023-09-26" @default.
- W1586984916 title "Controlled Light Exposure Microscopy" @default.
- W1586984916 cites W2017909074 @default.
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- W1586984916 doi "https://doi.org/10.1002/imic.200790220" @default.
- W1586984916 hasPublicationYear "2007" @default.
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