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- W158705429 abstract "This chapter focuses on optimal crossover designs. The principal idea associated with crossover designs is to use a number of available units for several measurements at different occasions. One possible motive for using a crossover design is that a crossover design requires fewer subjects for the same number of observations. This can obviously be an important consideration when subjects are scarce and when including a large number of subjects in the experiment can be prohibitively expensive. Another possible motive for using crossover designs is that these designs provide within subject information about treatment differences. In many applications, the different subjects would exhibit large natural differences, and inferences concerning treatment comparisons based on between subject information—available if subject effects are assumed to be random effects—would require a much larger replication of the treatments to achieve the same precision as inferences based on within subject information." @default.
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- W158705429 date "1996-01-01" @default.
- W158705429 modified "2023-09-28" @default.
- W158705429 title "3 Optimal crossover designs" @default.
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- W158705429 doi "https://doi.org/10.1016/s0169-7161(96)13005-4" @default.
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