Matches in SemOpenAlex for { <https://semopenalex.org/work/W1587445981> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W1587445981 abstract "Pain is a prevalent problem that can raise morbidity of patients. Pain killer releasing biodegradable materials have been developed by using different techniques and biomaterials. The objective of the current study is to evaluate the use of a new bioerodible polymer for release of diclofenac sodium (DS). 1‐butanol hemiester poly(maleic anhydride‐alt‐2‐methoxyethyl vinyl ether) (PAM14) was prepared in the university of Pisa and selected as polymer of choice for the study. Polymer solutions of 5–10% (in ethanol or in acetic acid) were prepared, half of them containing 2% DS. The solutions were then electrospun to produce nanomats that were subsequently characterized using SEM. Fiber diameter was 160 nm 1 μm. Increasing polymer concentration increased the size of the fibers but reduced the number of beads (with or without DS). In the specimens obtained from acetic acid solution, the addition of DS resulted in a reduction in fiber diameter and an increase in the inter‐bead distance. Corresponding ethanol solutions gave more homogeneous specimens than did acetic acid, having a lower number of beads. With the addition of DS a reduction in fiber diameter was observed for the acetic acid specimens. However, in ethanol, adding DS resulted in increased fiber diameter. Accordingly, it can be concluded that it is feasible to develop electrospun diclofenac releasing bioerodible nanostructures that have potential use in pain management. Their further evaluation is however, needed both in vitro and in vivo." @default.
- W1587445981 created "2016-06-24" @default.
- W1587445981 creator A5018926777 @default.
- W1587445981 creator A5026372960 @default.
- W1587445981 creator A5038868193 @default.
- W1587445981 creator A5068665739 @default.
- W1587445981 creator A5079059039 @default.
- W1587445981 date "2008-01-01" @default.
- W1587445981 modified "2023-09-26" @default.
- W1587445981 title "Diclofenac sodium (DS) loaded bioerodible polymer based constructs" @default.
- W1587445981 cites W2099080420 @default.
- W1587445981 doi "https://doi.org/10.1063/1.2896915" @default.
- W1587445981 hasPublicationYear "2008" @default.
- W1587445981 type Work @default.
- W1587445981 sameAs 1587445981 @default.
- W1587445981 citedByCount "0" @default.
- W1587445981 crossrefType "proceedings-article" @default.
- W1587445981 hasAuthorship W1587445981A5018926777 @default.
- W1587445981 hasAuthorship W1587445981A5026372960 @default.
- W1587445981 hasAuthorship W1587445981A5038868193 @default.
- W1587445981 hasAuthorship W1587445981A5068665739 @default.
- W1587445981 hasAuthorship W1587445981A5079059039 @default.
- W1587445981 hasConcept C13965031 @default.
- W1587445981 hasConcept C15920480 @default.
- W1587445981 hasConcept C159985019 @default.
- W1587445981 hasConcept C161790260 @default.
- W1587445981 hasConcept C178790620 @default.
- W1587445981 hasConcept C185592680 @default.
- W1587445981 hasConcept C192562407 @default.
- W1587445981 hasConcept C2776673659 @default.
- W1587445981 hasConcept C2779854550 @default.
- W1587445981 hasConcept C2780161600 @default.
- W1587445981 hasConcept C2781206178 @default.
- W1587445981 hasConcept C2908765736 @default.
- W1587445981 hasConcept C43617362 @default.
- W1587445981 hasConcept C519885992 @default.
- W1587445981 hasConcept C521977710 @default.
- W1587445981 hasConcept C91129048 @default.
- W1587445981 hasConceptScore W1587445981C13965031 @default.
- W1587445981 hasConceptScore W1587445981C15920480 @default.
- W1587445981 hasConceptScore W1587445981C159985019 @default.
- W1587445981 hasConceptScore W1587445981C161790260 @default.
- W1587445981 hasConceptScore W1587445981C178790620 @default.
- W1587445981 hasConceptScore W1587445981C185592680 @default.
- W1587445981 hasConceptScore W1587445981C192562407 @default.
- W1587445981 hasConceptScore W1587445981C2776673659 @default.
- W1587445981 hasConceptScore W1587445981C2779854550 @default.
- W1587445981 hasConceptScore W1587445981C2780161600 @default.
- W1587445981 hasConceptScore W1587445981C2781206178 @default.
- W1587445981 hasConceptScore W1587445981C2908765736 @default.
- W1587445981 hasConceptScore W1587445981C43617362 @default.
- W1587445981 hasConceptScore W1587445981C519885992 @default.
- W1587445981 hasConceptScore W1587445981C521977710 @default.
- W1587445981 hasConceptScore W1587445981C91129048 @default.
- W1587445981 hasLocation W15874459811 @default.
- W1587445981 hasOpenAccess W1587445981 @default.
- W1587445981 hasPrimaryLocation W15874459811 @default.
- W1587445981 hasRelatedWork W1023617215 @default.
- W1587445981 hasRelatedWork W1979349473 @default.
- W1587445981 hasRelatedWork W2097352990 @default.
- W1587445981 hasRelatedWork W2353325021 @default.
- W1587445981 hasRelatedWork W2357993680 @default.
- W1587445981 hasRelatedWork W2373519318 @default.
- W1587445981 hasRelatedWork W259443419 @default.
- W1587445981 hasRelatedWork W2748952813 @default.
- W1587445981 hasRelatedWork W2899084033 @default.
- W1587445981 hasRelatedWork W4256365620 @default.
- W1587445981 isParatext "false" @default.
- W1587445981 isRetracted "false" @default.
- W1587445981 magId "1587445981" @default.
- W1587445981 workType "article" @default.