Matches in SemOpenAlex for { <https://semopenalex.org/work/W1587695583> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W1587695583 abstract "A method was developed for the simultaneous extraction and determination of four mercapturic acids (MAs), N-acetyl-S-(3,4-dihydroxybutyl)-L-cysteine (DHBMA), N-acetyl-S-(3-hydroxypropyl)-L-cysteine (3-HPMA), N-acetyl-S-(2-carboxyethyl)-L-cysteine ( CEMA) and S-phenylmercapturic acid (SPMA), in human urine using solid phase extraction and high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). Frozen urine samples were thawed at room temperature, and centrifuged to remove any settled precipitate. The supernatant was then purified and concentrated by a C18 solid phase extraction column, and analyzed by HPLC-MS/MS in the multiple reaction monitoring (MRM) mode for the quantitative analysis. The ranges of recovery for DHBMA, 3-HPMA, CEMA and SPMA spiked in human urine matrix at three concentration levels were 105.6%-124.4%, 102.7%-106.5%, 103.2%-103.9% and 101.7%-104.3%, respectively, with the relative standard deviations of 2.6%-7.7%. The limits of detection (LOD, S/N > or = 3) were 0. 062, 0. 031, 0. 020 and 0. 003 microg/L for DHBMA, 3-HPMA, CEMA and SPMA, respectively. The method was successfully used to detect 4 MAs in 37 human urine samples from smokers and non-smokers. It was found that the contents of 3-HPMA, CEMA and SPMA in the urines from cigarette smokers were about three to six-fold more than those in the urines from the non-smokers." @default.
- W1587695583 created "2016-06-24" @default.
- W1587695583 creator A5010787304 @default.
- W1587695583 creator A5012142025 @default.
- W1587695583 creator A5034255213 @default.
- W1587695583 creator A5040913973 @default.
- W1587695583 creator A5043886610 @default.
- W1587695583 creator A5091039278 @default.
- W1587695583 date "2011-03-02" @default.
- W1587695583 modified "2023-09-25" @default.
- W1587695583 title "Simultaneous determination of four mercapturic acids in human urine using solid phase extraction and liquid chromatography-tandem mass spectrometry" @default.
- W1587695583 cites W1966382273 @default.
- W1587695583 cites W1982969180 @default.
- W1587695583 cites W1988980950 @default.
- W1587695583 cites W2032303437 @default.
- W1587695583 cites W2053024028 @default.
- W1587695583 cites W2064847075 @default.
- W1587695583 cites W2068718322 @default.
- W1587695583 cites W2132051961 @default.
- W1587695583 doi "https://doi.org/10.3724/sp.j.1123.2011.00031" @default.
- W1587695583 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21574397" @default.
- W1587695583 hasPublicationYear "2011" @default.
- W1587695583 type Work @default.
- W1587695583 sameAs 1587695583 @default.
- W1587695583 citedByCount "0" @default.
- W1587695583 crossrefType "journal-article" @default.
- W1587695583 hasAuthorship W1587695583A5010787304 @default.
- W1587695583 hasAuthorship W1587695583A5012142025 @default.
- W1587695583 hasAuthorship W1587695583A5034255213 @default.
- W1587695583 hasAuthorship W1587695583A5040913973 @default.
- W1587695583 hasAuthorship W1587695583A5043886610 @default.
- W1587695583 hasAuthorship W1587695583A5091039278 @default.
- W1587695583 hasConcept C119128265 @default.
- W1587695583 hasConcept C162356407 @default.
- W1587695583 hasConcept C179998833 @default.
- W1587695583 hasConcept C185592680 @default.
- W1587695583 hasConcept C2780026642 @default.
- W1587695583 hasConcept C31827203 @default.
- W1587695583 hasConcept C43617362 @default.
- W1587695583 hasConcept C4725764 @default.
- W1587695583 hasConcept C55493867 @default.
- W1587695583 hasConcept C81426234 @default.
- W1587695583 hasConcept C95986675 @default.
- W1587695583 hasConceptScore W1587695583C119128265 @default.
- W1587695583 hasConceptScore W1587695583C162356407 @default.
- W1587695583 hasConceptScore W1587695583C179998833 @default.
- W1587695583 hasConceptScore W1587695583C185592680 @default.
- W1587695583 hasConceptScore W1587695583C2780026642 @default.
- W1587695583 hasConceptScore W1587695583C31827203 @default.
- W1587695583 hasConceptScore W1587695583C43617362 @default.
- W1587695583 hasConceptScore W1587695583C4725764 @default.
- W1587695583 hasConceptScore W1587695583C55493867 @default.
- W1587695583 hasConceptScore W1587695583C81426234 @default.
- W1587695583 hasConceptScore W1587695583C95986675 @default.
- W1587695583 hasLocation W15876955831 @default.
- W1587695583 hasLocation W15876955832 @default.
- W1587695583 hasOpenAccess W1587695583 @default.
- W1587695583 hasPrimaryLocation W15876955831 @default.
- W1587695583 hasRelatedWork W1966382273 @default.
- W1587695583 hasRelatedWork W1975214644 @default.
- W1587695583 hasRelatedWork W2004211469 @default.
- W1587695583 hasRelatedWork W2018184834 @default.
- W1587695583 hasRelatedWork W2032580297 @default.
- W1587695583 hasRelatedWork W2042196153 @default.
- W1587695583 hasRelatedWork W2052698264 @default.
- W1587695583 hasRelatedWork W2057180245 @default.
- W1587695583 hasRelatedWork W2058813190 @default.
- W1587695583 hasRelatedWork W2071214511 @default.
- W1587695583 hasRelatedWork W2088063041 @default.
- W1587695583 hasRelatedWork W2170936760 @default.
- W1587695583 hasRelatedWork W2349167392 @default.
- W1587695583 hasRelatedWork W2350120634 @default.
- W1587695583 hasRelatedWork W2354486352 @default.
- W1587695583 hasRelatedWork W2361247111 @default.
- W1587695583 hasRelatedWork W2378910171 @default.
- W1587695583 hasRelatedWork W2494099090 @default.
- W1587695583 hasRelatedWork W2559644544 @default.
- W1587695583 hasRelatedWork W2131982694 @default.
- W1587695583 isParatext "false" @default.
- W1587695583 isRetracted "false" @default.
- W1587695583 magId "1587695583" @default.
- W1587695583 workType "article" @default.