Matches in SemOpenAlex for { <https://semopenalex.org/work/W1588056616> ?p ?o ?g. }
- W1588056616 endingPage "613" @default.
- W1588056616 startingPage "610" @default.
- W1588056616 abstract "What is known and objective: Serotonin syndrome can be a rare but life-threatening condition that is commonly the result of a drug–drug interaction causing excessive serotonin activity. The symptoms associated with serotonin syndrome can include hyperthermia, mental status changes, autonomic hyperactivity and neuromuscular abnormalities, all of which can be concealed in the critically ill patient owing to concomitant therapies. The objective of this case report is to describe a probable drug–drug interaction between buspirone and linezolid, and to highlight the potential confounding effects of hypothermia in this case. Case summary: We present a case of a 28-year-old man who potentially developed serotonin syndrome after coadministration of buspirone and linezolid while being therapeutically cooled for traumatic brain injury. The patient developed hyperthermia, hypertension and tachycardia when buspirone and linezolid were administered concomitantly for 2 days. Symptoms resolved within 24 h after discontinuation of both medications. What is new and conclusions: Caution should be used in patients receiving multiple serotonergic agents in addition to therapeutic hypothermia. The use of therapeutic hypothermia may mask the symptoms associated with serotonin syndrome, thus delaying the diagnosis and treatment of this potentially deadly condition. If a patient requires the combination of such medications, close monitoring for the symptoms of serotonin syndrome is warranted." @default.
- W1588056616 created "2016-06-24" @default.
- W1588056616 creator A5053312507 @default.
- W1588056616 creator A5058772313 @default.
- W1588056616 date "2012-03-27" @default.
- W1588056616 modified "2023-09-26" @default.
- W1588056616 title "Probable drug-drug interaction leading to serotonin syndrome in a patient treated with concomitant buspirone and linezolid in the setting of therapeutic hypothermia" @default.
- W1588056616 cites W1983189665 @default.
- W1588056616 cites W1984912665 @default.
- W1588056616 cites W1988279180 @default.
- W1588056616 cites W2014447012 @default.
- W1588056616 cites W2045573334 @default.
- W1588056616 cites W2045916447 @default.
- W1588056616 cites W2067717797 @default.
- W1588056616 cites W2067978628 @default.
- W1588056616 cites W2073012550 @default.
- W1588056616 cites W2083499338 @default.
- W1588056616 cites W2108934165 @default.
- W1588056616 cites W2109917815 @default.
- W1588056616 cites W2116532521 @default.
- W1588056616 cites W2123238440 @default.
- W1588056616 cites W2123778879 @default.
- W1588056616 cites W2126497639 @default.
- W1588056616 cites W2143024370 @default.
- W1588056616 cites W2156076829 @default.
- W1588056616 cites W2167496369 @default.
- W1588056616 cites W2169199785 @default.
- W1588056616 doi "https://doi.org/10.1111/j.1365-2710.2012.01344.x" @default.
- W1588056616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22452676" @default.
- W1588056616 hasPublicationYear "2012" @default.
- W1588056616 type Work @default.
- W1588056616 sameAs 1588056616 @default.
- W1588056616 citedByCount "12" @default.
- W1588056616 countsByYear W15880566162013 @default.
- W1588056616 countsByYear W15880566162014 @default.
- W1588056616 countsByYear W15880566162015 @default.
- W1588056616 countsByYear W15880566162016 @default.
- W1588056616 countsByYear W15880566162017 @default.
- W1588056616 countsByYear W15880566162018 @default.
- W1588056616 crossrefType "journal-article" @default.
- W1588056616 hasAuthorship W1588056616A5053312507 @default.
- W1588056616 hasAuthorship W1588056616A5058772313 @default.
- W1588056616 hasBestOaLocation W15880566161 @default.
- W1588056616 hasConcept C126322002 @default.
- W1588056616 hasConcept C170493617 @default.
- W1588056616 hasConcept C177713679 @default.
- W1588056616 hasConcept C2775864247 @default.
- W1588056616 hasConcept C2777287423 @default.
- W1588056616 hasConcept C2777390192 @default.
- W1588056616 hasConcept C2777964233 @default.
- W1588056616 hasConcept C2778715236 @default.
- W1588056616 hasConcept C2778980435 @default.
- W1588056616 hasConcept C2779384505 @default.
- W1588056616 hasConcept C2779489039 @default.
- W1588056616 hasConcept C2780035454 @default.
- W1588056616 hasConcept C2780179036 @default.
- W1588056616 hasConcept C2781414143 @default.
- W1588056616 hasConcept C37000724 @default.
- W1588056616 hasConcept C42219234 @default.
- W1588056616 hasConcept C523546767 @default.
- W1588056616 hasConcept C54355233 @default.
- W1588056616 hasConcept C71924100 @default.
- W1588056616 hasConcept C86803240 @default.
- W1588056616 hasConcept C98274493 @default.
- W1588056616 hasConceptScore W1588056616C126322002 @default.
- W1588056616 hasConceptScore W1588056616C170493617 @default.
- W1588056616 hasConceptScore W1588056616C177713679 @default.
- W1588056616 hasConceptScore W1588056616C2775864247 @default.
- W1588056616 hasConceptScore W1588056616C2777287423 @default.
- W1588056616 hasConceptScore W1588056616C2777390192 @default.
- W1588056616 hasConceptScore W1588056616C2777964233 @default.
- W1588056616 hasConceptScore W1588056616C2778715236 @default.
- W1588056616 hasConceptScore W1588056616C2778980435 @default.
- W1588056616 hasConceptScore W1588056616C2779384505 @default.
- W1588056616 hasConceptScore W1588056616C2779489039 @default.
- W1588056616 hasConceptScore W1588056616C2780035454 @default.
- W1588056616 hasConceptScore W1588056616C2780179036 @default.
- W1588056616 hasConceptScore W1588056616C2781414143 @default.
- W1588056616 hasConceptScore W1588056616C37000724 @default.
- W1588056616 hasConceptScore W1588056616C42219234 @default.
- W1588056616 hasConceptScore W1588056616C523546767 @default.
- W1588056616 hasConceptScore W1588056616C54355233 @default.
- W1588056616 hasConceptScore W1588056616C71924100 @default.
- W1588056616 hasConceptScore W1588056616C86803240 @default.
- W1588056616 hasConceptScore W1588056616C98274493 @default.
- W1588056616 hasIssue "5" @default.
- W1588056616 hasLocation W15880566161 @default.
- W1588056616 hasLocation W15880566162 @default.
- W1588056616 hasOpenAccess W1588056616 @default.
- W1588056616 hasPrimaryLocation W15880566161 @default.
- W1588056616 hasRelatedWork W1588056616 @default.
- W1588056616 hasRelatedWork W2123238440 @default.
- W1588056616 hasRelatedWork W2156076829 @default.
- W1588056616 hasRelatedWork W2167496369 @default.
- W1588056616 hasRelatedWork W2226628527 @default.
- W1588056616 hasRelatedWork W2290809453 @default.
- W1588056616 hasRelatedWork W2810551190 @default.
- W1588056616 hasRelatedWork W2995715290 @default.