FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1588061731> ?p ?o ?g. }

• W1588061731 endingPage "69" @default.
• W1588061731 startingPage "62" @default.
• W1588061731 abstract "A cAMP and some glucocorticoid response elements have been underlined in the promoter of mouse annexin A1. To analyse the function of these DNA sequences, the role of cAMP and glucocorticoids, as well as the transcription factors involved in their activation, were investigated. A construct containing 1381 bp of the DNA 5'-flanking annexin A1 gene fused to LacZ was used. The level of activation of the reporter gene was analysed by transient transfection of the JEG3 cell line. Activation of beta-galactosidase expression was observed with both dibutyryl cAMP and dexamethasone when compared with cells treated with serum only. Simultaneous addition of dexamethasone and dibutyryl cAMP did not result in a synergistic effect but rather in a competitive one. Gel-shift assays with a probe including the cAMP response element-like element of the annexin A1 promoter revealed a main specific DNA-protein complex when cells were stimulated with dibutyryl cAMP and/or dexamethasone. In all cases CREB protein was identified by supershift analysis. We therefore conclude that this cAMP response element sequence plays a prominent role in the transactivation of the annexin A1 promoter by dibutyryl cAMP and that it is involved in the response to glucocorticoids." @default.
• W1588061731 created "2016-06-24" @default.
• W1588061731 creator A5004961174 @default.
• W1588061731 creator A5006000485 @default.
• W1588061731 creator A5053037768 @default.
• W1588061731 creator A5054823580 @default.
• W1588061731 date "2001-01-01" @default.
• W1588061731 modified "2023-09-25" @default.
• W1588061731 title "CREB is involved in mouse annexin A1 regulation by cAMP and glucocorticoids" @default.
• W1588061731 cites W1569934864 @default.
• W1588061731 cites W1788924459 @default.
• W1588061731 cites W1874865406 @default.
• W1588061731 cites W1965372133 @default.
• W1588061731 cites W1969935465 @default.
• W1588061731 cites W1974206605 @default.
• W1588061731 cites W1979553328 @default.
• W1588061731 cites W1984021794 @default.
• W1588061731 cites W1985605578 @default.
• W1588061731 cites W1991208631 @default.
• W1588061731 cites W1993243592 @default.
• W1588061731 cites W2014669590 @default.
• W1588061731 cites W2016066271 @default.
• W1588061731 cites W2017859874 @default.
• W1588061731 cites W2018213065 @default.
• W1588061731 cites W2028242823 @default.
• W1588061731 cites W2032379826 @default.
• W1588061731 cites W2036602491 @default.
• W1588061731 cites W2036692598 @default.
• W1588061731 cites W2036993706 @default.
• W1588061731 cites W2051278059 @default.
• W1588061731 cites W2066108810 @default.
• W1588061731 cites W2068970565 @default.
• W1588061731 cites W2078002794 @default.
• W1588061731 cites W2078690661 @default.
• W1588061731 cites W2079295410 @default.
• W1588061731 cites W2085292543 @default.
• W1588061731 cites W2097228095 @default.
• W1588061731 cites W2097794242 @default.
• W1588061731 cites W2169653086 @default.
• W1588061731 cites W30701984 @default.
• W1588061731 cites W4248079573 @default.
• W1588061731 cites W4252918925 @default.
• W1588061731 cites W4293247451 @default.
• W1588061731 doi "https://doi.org/10.1046/j.1432-1327.2001.01840.x" @default.
• W1588061731 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11121103" @default.
• W1588061731 hasPublicationYear "2001" @default.
• W1588061731 type Work @default.
• W1588061731 sameAs 1588061731 @default.
• W1588061731 citedByCount "18" @default.
• W1588061731 countsByYear W15880617312012 @default.
• W1588061731 countsByYear W15880617312017 @default.
• W1588061731 countsByYear W15880617312019 @default.
• W1588061731 countsByYear W15880617312020 @default.
• W1588061731 countsByYear W15880617312023 @default.
• W1588061731 crossrefType "journal-article" @default.
• W1588061731 hasAuthorship W1588061731A5004961174 @default.
• W1588061731 hasAuthorship W1588061731A5006000485 @default.
• W1588061731 hasAuthorship W1588061731A5053037768 @default.
• W1588061731 hasAuthorship W1588061731A5054823580 @default.
• W1588061731 hasConcept C101762097 @default.
• W1588061731 hasConcept C104317684 @default.
• W1588061731 hasConcept C1292079 @default.
• W1588061731 hasConcept C132376346 @default.
• W1588061731 hasConcept C134018914 @default.
• W1588061731 hasConcept C138885662 @default.
• W1588061731 hasConcept C150194340 @default.
• W1588061731 hasConcept C153911025 @default.
• W1588061731 hasConcept C161733203 @default.
• W1588061731 hasConcept C1629964 @default.
• W1588061731 hasConcept C179926584 @default.
• W1588061731 hasConcept C199172495 @default.
• W1588061731 hasConcept C2780841215 @default.
• W1588061731 hasConcept C41895202 @default.
• W1588061731 hasConcept C54009773 @default.
• W1588061731 hasConcept C553184892 @default.
• W1588061731 hasConcept C55493867 @default.
• W1588061731 hasConcept C86339819 @default.
• W1588061731 hasConcept C86803240 @default.
• W1588061731 hasConcept C88634738 @default.
• W1588061731 hasConceptScore W1588061731C101762097 @default.
• W1588061731 hasConceptScore W1588061731C104317684 @default.
• W1588061731 hasConceptScore W1588061731C1292079 @default.
• W1588061731 hasConceptScore W1588061731C132376346 @default.
• W1588061731 hasConceptScore W1588061731C134018914 @default.
• W1588061731 hasConceptScore W1588061731C138885662 @default.
• W1588061731 hasConceptScore W1588061731C150194340 @default.
• W1588061731 hasConceptScore W1588061731C153911025 @default.
• W1588061731 hasConceptScore W1588061731C161733203 @default.
• W1588061731 hasConceptScore W1588061731C1629964 @default.
• W1588061731 hasConceptScore W1588061731C179926584 @default.
• W1588061731 hasConceptScore W1588061731C199172495 @default.
• W1588061731 hasConceptScore W1588061731C2780841215 @default.
• W1588061731 hasConceptScore W1588061731C41895202 @default.
• W1588061731 hasConceptScore W1588061731C54009773 @default.
• W1588061731 hasConceptScore W1588061731C553184892 @default.
• W1588061731 hasConceptScore W1588061731C55493867 @default.
• W1588061731 hasConceptScore W1588061731C86339819 @default.
• W1588061731 hasConceptScore W1588061731C86803240 @default.

• next