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- W1588109258 abstract "Publisher Summary This chapter reviews the general aspects of cellular aging to serve as a common background for discussions on aging of specific cells, systems, and functions. A review of the demography of aging highlighted the current urgency of the study of gerontology and geriatrics. Life expectancy has dramatically lengthened in this century, with a marked increase in the percentage of the elderly human populations worldwide, and it is expected that this trend will continue well into the next century. Among the many important areas of study, the identification of the genetic and physiological characteristics that differentiate “successful” from “usual” aging promises both basic and practical advances in the understanding of cellular and organismic aging. However, even successful aging is associated with progressive functional impairment and increasing incidence and severity of pathology and disease. The chapter focuses on the major types of cell pathology, cell injury, and cell death. The principal theories of aging are examined in the chapter. It is suggested that, at least in complex organisms such as humans, several factors, genetic and environmental, acting at the molecular, cellular, and organismic levels contribute to survival and longevity." @default.
- W1588109258 created "2016-06-24" @default.
- W1588109258 creator A5049646526 @default.
- W1588109258 date "1996-01-01" @default.
- W1588109258 modified "2023-09-27" @default.
- W1588109258 title "Chapter 1 The Cell Aging Process" @default.
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