Matches in SemOpenAlex for { <https://semopenalex.org/work/W1588312516> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W1588312516 endingPage "4107" @default.
- W1588312516 startingPage "4103" @default.
- W1588312516 abstract "Abstract In the present study, the contribution of IFN-gamma to the generation of helper activity in mice was investigated by use of anti-mouse IFN-gamma rat mAB (AN 18.17.24). This mAb was alum precipitated and injected i.p. before or after carrier priming. Results show that spleen cell helper activity is markedly inhibited by anti-IFN-gamma mAb injection. This inhibition is time and dose dependent, and counteracted by IFN-gamma administration. Thus, the anti-IFN-gamma mAb appears to inhibit helper cell activity by neutralization of the IFN-gamma required for the antibody response. Moreover, AN 18.17.24 mAb injection results in increased activation of Lyt-2+ T cells which markedly suppress Th activity. These findings altogether indicate that besides the activation of macrophages and Th, IFN-gamma seems to exert a negative interference in suppressor T lymphocyte circuits and, as a consequence, to inhibit immunosuppression." @default.
- W1588312516 created "2016-06-24" @default.
- W1588312516 creator A5021850748 @default.
- W1588312516 creator A5024383373 @default.
- W1588312516 creator A5030792723 @default.
- W1588312516 creator A5058458204 @default.
- W1588312516 date "1988-06-15" @default.
- W1588312516 modified "2023-10-16" @default.
- W1588312516 title "Enhancement of suppressor T cell activity by injection of anti-IFN-gamma monoclonal antibody." @default.
- W1588312516 doi "https://doi.org/10.4049/jimmunol.140.12.4103" @default.
- W1588312516 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2967327" @default.
- W1588312516 hasPublicationYear "1988" @default.
- W1588312516 type Work @default.
- W1588312516 sameAs 1588312516 @default.
- W1588312516 citedByCount "7" @default.
- W1588312516 crossrefType "journal-article" @default.
- W1588312516 hasAuthorship W1588312516A5021850748 @default.
- W1588312516 hasAuthorship W1588312516A5024383373 @default.
- W1588312516 hasAuthorship W1588312516A5030792723 @default.
- W1588312516 hasAuthorship W1588312516A5058458204 @default.
- W1588312516 hasConcept C100701293 @default.
- W1588312516 hasConcept C104317684 @default.
- W1588312516 hasConcept C153911025 @default.
- W1588312516 hasConcept C159654299 @default.
- W1588312516 hasConcept C179185449 @default.
- W1588312516 hasConcept C185592680 @default.
- W1588312516 hasConcept C203014093 @default.
- W1588312516 hasConcept C2776090121 @default.
- W1588312516 hasConcept C2778690821 @default.
- W1588312516 hasConcept C2780841837 @default.
- W1588312516 hasConcept C2780931953 @default.
- W1588312516 hasConcept C2992881475 @default.
- W1588312516 hasConcept C542903549 @default.
- W1588312516 hasConcept C55493867 @default.
- W1588312516 hasConcept C59822182 @default.
- W1588312516 hasConcept C81444415 @default.
- W1588312516 hasConcept C86803240 @default.
- W1588312516 hasConcept C8891405 @default.
- W1588312516 hasConceptScore W1588312516C100701293 @default.
- W1588312516 hasConceptScore W1588312516C104317684 @default.
- W1588312516 hasConceptScore W1588312516C153911025 @default.
- W1588312516 hasConceptScore W1588312516C159654299 @default.
- W1588312516 hasConceptScore W1588312516C179185449 @default.
- W1588312516 hasConceptScore W1588312516C185592680 @default.
- W1588312516 hasConceptScore W1588312516C203014093 @default.
- W1588312516 hasConceptScore W1588312516C2776090121 @default.
- W1588312516 hasConceptScore W1588312516C2778690821 @default.
- W1588312516 hasConceptScore W1588312516C2780841837 @default.
- W1588312516 hasConceptScore W1588312516C2780931953 @default.
- W1588312516 hasConceptScore W1588312516C2992881475 @default.
- W1588312516 hasConceptScore W1588312516C542903549 @default.
- W1588312516 hasConceptScore W1588312516C55493867 @default.
- W1588312516 hasConceptScore W1588312516C59822182 @default.
- W1588312516 hasConceptScore W1588312516C81444415 @default.
- W1588312516 hasConceptScore W1588312516C86803240 @default.
- W1588312516 hasConceptScore W1588312516C8891405 @default.
- W1588312516 hasIssue "12" @default.
- W1588312516 hasLocation W15883125161 @default.
- W1588312516 hasLocation W15883125162 @default.
- W1588312516 hasOpenAccess W1588312516 @default.
- W1588312516 hasPrimaryLocation W15883125161 @default.
- W1588312516 hasRelatedWork W1542757290 @default.
- W1588312516 hasRelatedWork W1981011272 @default.
- W1588312516 hasRelatedWork W1992169430 @default.
- W1588312516 hasRelatedWork W2009889818 @default.
- W1588312516 hasRelatedWork W2014861510 @default.
- W1588312516 hasRelatedWork W2024399865 @default.
- W1588312516 hasRelatedWork W2063428357 @default.
- W1588312516 hasRelatedWork W2343991547 @default.
- W1588312516 hasRelatedWork W2368460920 @default.
- W1588312516 hasRelatedWork W2380360044 @default.
- W1588312516 hasVolume "140" @default.
- W1588312516 isParatext "false" @default.
- W1588312516 isRetracted "false" @default.
- W1588312516 magId "1588312516" @default.
- W1588312516 workType "article" @default.