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- W1588458127 abstract "Cerebral palsy (CP) is a group of disorders characterised by motor and/or postural dysfunction of a non-progressive nature commonly associated with cognitive impairment. The prevalence of CP is 2/1,000 live births, with principal obstetric risk factors being preterm birth (particularly less than 34 weeks) and very low birth weight (less than 1,500g). Approximately 42% of all cases of CP are associated with preterm birth (Australian Cerebral Palsy Register Group) with the rate of disorders amongst neonatal survivors born at less than 28 weeks gestation up to 30 times higher compared with infants born at term. CP has a severe impact for the health care system. In Australia, for example, the cost of CP to the Australian community is around US$3.8 billion per annum. The Centers of Disease Control and Prevention estimates the lifetime costs – including direct medical (physician visits, hospital stays, medication, assistive devices, long-term care), direct nonmedical (home and automobile modifications, special education), and indirect (productivity loses) – for all people born with CP in 2000 to be $11.5 billion. The estimated lifetime cost of CP is US$1 million per case. To date, there have been limited antenatal strategies to prevent this devastating outcome, but encouraging results from meta-analysis using several large and well-designed trials confirm that administration of magnesium sulphate (MgSO 4 ) improves the neurodevelopmental future of preterm infants." @default.
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- W1588458127 date "2011-06-01" @default.
- W1588458127 modified "2023-09-23" @default.
- W1588458127 title "Magnesium sulphate for fetal neuroprotection." @default.
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