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• W1588907105 abstract "The encapsulated fungal pathogens Cryptococcus neoformans and Cryptococcus gattii are significant agents of life-threatening infections, particularly in persons with suppressed cell-mediated immunity. This chapter provides detailed methodology for the purification of two of the major antigen fractions of C. neoformans: glucuronoxylomannan (GXM) and mannoprotein (MP). GXM is the primary component of the polysaccharide capsule, which is the major cryptococcal virulence factor. In contrast, MPs have been identified as key antigens that stimulate T-cell responses. Purification of GXM and MP should assist investigators studying the antigenic, biochemical, and virulence properties of Cryptococcus species." @default.
• W1588907105 created "2016-06-24" @default.
• W1588907105 creator A5050851557 @default.
• W1588907105 creator A5054141043 @default.
• W1588907105 date "2009-01-01" @default.
• W1588907105 modified "2023-10-13" @default.
• W1588907105 title "Isolation and Purification of Antigenic Components of Cryptococcus" @default.
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• W1588907105 doi "https://doi.org/10.1007/978-1-59745-204-5_7" @default.
• W1588907105 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3297022" @default.
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