FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1589005448> ?p ?o ?g. }

• W1589005448 endingPage "1" @default.
• W1589005448 startingPage "1" @default.
• W1589005448 abstract "BACKGROUND: The use of antithrombotic agents and falls are independently associated with an increased risk of hemorrhagic injury. However, few studies have delineated the risk of fall-related hemorrhagic complications in persons who are taking antithrombotic therapy. The objective of this study was to compare the rates of fall-related hemorrhagic injury in hospital in-patients who are taking and not taking antithrombotic therapy. METHODS: A 4-year retrospective chart review of consecutive patients who fell during admission to a 500-bed tertiary-care teaching hospital was conducted. Major hemorrhagic injuries including subdural hematomas and major bleeding/cuts, patients' use of antithrombotic medication (warfarin, aspirin, clopidogrel and heparin) and their anticoagulation status at the time of their fall were recorded. RESULTS: A total of 2635 falls in 1861 patients were reviewed. Approximately 10% of falls caused major hemorrhagic injury. One fall resulted in a subdural hematoma. Persons taking warfarin were less likely to suffer a fall-related major hemorrhagic injury compared with persons not taking antithrombotic therapy (warfarin, 6%; no therapy, 11%; p = 0.01). Logistic regression showed that fall-related major hemorrhagic injury was associated with female gender (odds ratio 1.6; 95% CI 1.3, 2.1), use of aspirin (odds ratio 1.4; 95% CI 1.1, 1.8) and use of clopidogrel (odds ratio 2.2; 95% CI 1.1, 4.8), but not with the use of warfarin or heparin, or the intensity of anticoagulation. CONCLUSIONS: In this study, compared with persons taking no antithrombotic therapy, those taking warfarin had lower rates of fall-related hemorrhagic injuries. The absolute rate of the development of fall-related intracranial hemorrhagic injury such as subdural hematomas was low, even in persons taking warfarin. These counter-intuitive results may be due to selection bias, and suggest that physicians are very conservative in selecting patients for warfarin therapy, choosing only those who are sufficiently healthy to be at much lower than average risk of suffering fall-related hemorrhagic injuries. This phenomenon may lead to physicians overestimating the potential for fall-related major hemorrhagic injury in persons taking antithrombotic therapy, with the possible denial of warfarin therapy to many of those who would benefit. This perception may contribute to the care gap between the number of patients who would theoretically derive overall benefit from warfarin therapy and those who are actually receiving it." @default.
• W1589005448 created "2016-06-24" @default.
• W1589005448 creator A5001309926 @default.
• W1589005448 creator A5013766154 @default.
• W1589005448 creator A5026161206 @default.
• W1589005448 creator A5027169145 @default.
• W1589005448 creator A5091717122 @default.
• W1589005448 date "2005-01-01" @default.
• W1589005448 modified "2023-09-22" @default.
• W1589005448 cites W1968185839 @default.
• W1589005448 cites W1972771467 @default.
• W1589005448 cites W1981746689 @default.
• W1589005448 cites W2001411232 @default.
• W1589005448 cites W2007280418 @default.
• W1589005448 cites W2007564671 @default.
• W1589005448 cites W2009938720 @default.
• W1589005448 cites W2063207586 @default.
• W1589005448 cites W2073496233 @default.
• W1589005448 cites W2118654837 @default.
• W1589005448 cites W2121647405 @default.
• W1589005448 cites W2129962350 @default.
• W1589005448 cites W2135593392 @default.
• W1589005448 cites W2137835206 @default.
• W1589005448 cites W2270861330 @default.
• W1589005448 cites W2314358062 @default.
• W1589005448 cites W2322424896 @default.
• W1589005448 cites W2337130116 @default.
• W1589005448 cites W4241320471 @default.
• W1589005448 cites W4290747706 @default.
• W1589005448 doi "https://doi.org/10.1186/1477-9560-3-1" @default.
• W1589005448 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/545051" @default.
• W1589005448 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15638939" @default.
• W1589005448 hasPublicationYear "2005" @default.
• W1589005448 type Work @default.
• W1589005448 sameAs 1589005448 @default.
• W1589005448 citedByCount "41" @default.
• W1589005448 countsByYear W15890054482012 @default.
• W1589005448 countsByYear W15890054482013 @default.
• W1589005448 countsByYear W15890054482014 @default.
• W1589005448 countsByYear W15890054482015 @default.
• W1589005448 countsByYear W15890054482016 @default.
• W1589005448 countsByYear W15890054482017 @default.
• W1589005448 countsByYear W15890054482018 @default.
• W1589005448 countsByYear W15890054482019 @default.
• W1589005448 countsByYear W15890054482020 @default.
• W1589005448 countsByYear W15890054482022 @default.
• W1589005448 crossrefType "journal-article" @default.
• W1589005448 hasAuthorship W1589005448A5001309926 @default.
• W1589005448 hasAuthorship W1589005448A5013766154 @default.
• W1589005448 hasAuthorship W1589005448A5026161206 @default.
• W1589005448 hasAuthorship W1589005448A5027169145 @default.
• W1589005448 hasAuthorship W1589005448A5091717122 @default.
• W1589005448 hasBestOaLocation W15890054481 @default.
• W1589005448 hasConcept C126322002 @default.
• W1589005448 hasConcept C141071460 @default.
• W1589005448 hasConcept C156957248 @default.
• W1589005448 hasConcept C167135981 @default.
• W1589005448 hasConcept C2776301958 @default.
• W1589005448 hasConcept C2777015399 @default.
• W1589005448 hasConcept C2777628954 @default.
• W1589005448 hasConcept C2777849778 @default.
• W1589005448 hasConcept C2779161974 @default.
• W1589005448 hasConcept C2779662492 @default.
• W1589005448 hasConcept C42219234 @default.
• W1589005448 hasConcept C71924100 @default.
• W1589005448 hasConceptScore W1589005448C126322002 @default.
• W1589005448 hasConceptScore W1589005448C141071460 @default.
• W1589005448 hasConceptScore W1589005448C156957248 @default.
• W1589005448 hasConceptScore W1589005448C167135981 @default.
• W1589005448 hasConceptScore W1589005448C2776301958 @default.
• W1589005448 hasConceptScore W1589005448C2777015399 @default.
• W1589005448 hasConceptScore W1589005448C2777628954 @default.
• W1589005448 hasConceptScore W1589005448C2777849778 @default.
• W1589005448 hasConceptScore W1589005448C2779161974 @default.
• W1589005448 hasConceptScore W1589005448C2779662492 @default.
• W1589005448 hasConceptScore W1589005448C42219234 @default.
• W1589005448 hasConceptScore W1589005448C71924100 @default.
• W1589005448 hasIssue "1" @default.
• W1589005448 hasLocation W15890054481 @default.
• W1589005448 hasLocation W15890054482 @default.
• W1589005448 hasLocation W15890054483 @default.
• W1589005448 hasLocation W15890054484 @default.
• W1589005448 hasOpenAccess W1589005448 @default.
• W1589005448 hasPrimaryLocation W15890054481 @default.
• W1589005448 hasRelatedWork W1508862217 @default.
• W1589005448 hasRelatedWork W1606995491 @default.
• W1589005448 hasRelatedWork W1974609923 @default.
• W1589005448 hasRelatedWork W2031270414 @default.
• W1589005448 hasRelatedWork W2071508828 @default.
• W1589005448 hasRelatedWork W2330185220 @default.
• W1589005448 hasRelatedWork W2388134738 @default.
• W1589005448 hasRelatedWork W2888386364 @default.
• W1589005448 hasRelatedWork W3198971710 @default.
• W1589005448 hasRelatedWork W2230230054 @default.
• W1589005448 hasVolume "3" @default.
• W1589005448 isParatext "false" @default.
• W1589005448 isRetracted "false" @default.
• W1589005448 magId "1589005448" @default.

• next