FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W158943628> ?p ?o ?g. }

• W158943628 endingPage "244" @default.
• W158943628 startingPage "233" @default.
• W158943628 abstract "Here, we describe methods to prepare a mammalian expression plasmid encoding EGFP fused to the amino-terminus of human DNA topoisomerase IIα (Topo IIα) for use in studying the dynamics of Topo IIα in living cells. In previous studies, this plasmid was transfected into LLC-Pk cells, a porcine epithelial cell line that remains relatively flat during mitosis. After selection for stable integration, cells were cloned by serial dilution in microwells and used to grow a stable cell line expressing EGFP-Topo IIα; this cell line was termed LPk-GT2. Using photobleaching methods with conventional and patterned photobleaching, LPk-GT2 cells were used to demonstrate the rapid dynamics of Topo IIα exchange in both interphase nuclei and mitotic chromosomes. These rapid dynamics are dependent on enzyme activity since ICRF159, a catalytic inhibitor of Topo IIα, slows dynamics significantly. The methods utilized in these studies are described herein." @default.
• W158943628 created "2016-06-24" @default.
• W158943628 creator A5054956917 @default.
• W158943628 creator A5077954031 @default.
• W158943628 creator A5082029726 @default.
• W158943628 date "2009-01-01" @default.
• W158943628 modified "2023-09-26" @default.
• W158943628 title "The Dynamics of DNA Topoisomerase IIα in Living Cells" @default.
• W158943628 cites W1497849975 @default.
• W158943628 cites W1635552303 @default.
• W158943628 cites W1868383104 @default.
• W158943628 cites W1919687599 @default.
• W158943628 cites W1965136128 @default.
• W158943628 cites W1985376829 @default.
• W158943628 cites W1992935264 @default.
• W158943628 cites W1998582794 @default.
• W158943628 cites W2002297333 @default.
• W158943628 cites W2002493222 @default.
• W158943628 cites W2017183849 @default.
• W158943628 cites W2031242841 @default.
• W158943628 cites W2040132766 @default.
• W158943628 cites W2044142379 @default.
• W158943628 cites W2064156444 @default.
• W158943628 cites W2065744088 @default.
• W158943628 cites W2068688075 @default.
• W158943628 cites W2069151403 @default.
• W158943628 cites W2088006036 @default.
• W158943628 cites W2110513131 @default.
• W158943628 cites W2120518374 @default.
• W158943628 cites W2136946165 @default.
• W158943628 doi "https://doi.org/10.1007/978-1-60761-340-4_18" @default.
• W158943628 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2950002" @default.
• W158943628 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19763954" @default.
• W158943628 hasPublicationYear "2009" @default.
• W158943628 type Work @default.
• W158943628 sameAs 158943628 @default.
• W158943628 citedByCount "2" @default.
• W158943628 countsByYear W1589436282019 @default.
• W158943628 countsByYear W1589436282022 @default.
• W158943628 crossrefType "book-chapter" @default.
• W158943628 hasAuthorship W158943628A5054956917 @default.
• W158943628 hasAuthorship W158943628A5077954031 @default.
• W158943628 hasAuthorship W158943628A5082029726 @default.
• W158943628 hasBestOaLocation W1589436282 @default.
• W158943628 hasConcept C121332964 @default.
• W158943628 hasConcept C145912823 @default.
• W158943628 hasConcept C147897179 @default.
• W158943628 hasConcept C153911025 @default.
• W158943628 hasConcept C185592680 @default.
• W158943628 hasConcept C22744801 @default.
• W158943628 hasConcept C24890656 @default.
• W158943628 hasConcept C26659971 @default.
• W158943628 hasConcept C29452124 @default.
• W158943628 hasConcept C31332276 @default.
• W158943628 hasConcept C41625074 @default.
• W158943628 hasConcept C54009773 @default.
• W158943628 hasConcept C54355233 @default.
• W158943628 hasConcept C552990157 @default.
• W158943628 hasConcept C55493867 @default.
• W158943628 hasConcept C62520636 @default.
• W158943628 hasConcept C81885089 @default.
• W158943628 hasConcept C86803240 @default.
• W158943628 hasConcept C91881484 @default.
• W158943628 hasConcept C93304396 @default.
• W158943628 hasConcept C95444343 @default.
• W158943628 hasConceptScore W158943628C121332964 @default.
• W158943628 hasConceptScore W158943628C145912823 @default.
• W158943628 hasConceptScore W158943628C147897179 @default.
• W158943628 hasConceptScore W158943628C153911025 @default.
• W158943628 hasConceptScore W158943628C185592680 @default.
• W158943628 hasConceptScore W158943628C22744801 @default.
• W158943628 hasConceptScore W158943628C24890656 @default.
• W158943628 hasConceptScore W158943628C26659971 @default.
• W158943628 hasConceptScore W158943628C29452124 @default.
• W158943628 hasConceptScore W158943628C31332276 @default.
• W158943628 hasConceptScore W158943628C41625074 @default.
• W158943628 hasConceptScore W158943628C54009773 @default.
• W158943628 hasConceptScore W158943628C54355233 @default.
• W158943628 hasConceptScore W158943628C552990157 @default.
• W158943628 hasConceptScore W158943628C55493867 @default.
• W158943628 hasConceptScore W158943628C62520636 @default.
• W158943628 hasConceptScore W158943628C81885089 @default.
• W158943628 hasConceptScore W158943628C86803240 @default.
• W158943628 hasConceptScore W158943628C91881484 @default.
• W158943628 hasConceptScore W158943628C93304396 @default.
• W158943628 hasConceptScore W158943628C95444343 @default.
• W158943628 hasLocation W1589436281 @default.
• W158943628 hasLocation W1589436282 @default.
• W158943628 hasLocation W1589436283 @default.
• W158943628 hasLocation W1589436284 @default.
• W158943628 hasOpenAccess W158943628 @default.
• W158943628 hasPrimaryLocation W1589436281 @default.
• W158943628 hasRelatedWork W106631345 @default.
• W158943628 hasRelatedWork W1546299383 @default.
• W158943628 hasRelatedWork W158943628 @default.
• W158943628 hasRelatedWork W1995230172 @default.
• W158943628 hasRelatedWork W2035842805 @default.
• W158943628 hasRelatedWork W2119386820 @default.

• next