FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1589818568> ?p ?o ?g. }

• W1589818568 abstract "Litter size and birth weights are limited by uterine capacity, defined as the ability of the uterus to maintain the appropriate development of some number of conceptuses. Uterine capacity is the result of the combined effects of uterine, placental and embryo/fetal function. The number of living conceptuses that the uterus is capable of supporting is greater during early gestation compared to later gestation. Plots of log fetal weight versus log placental weight also indicate that fetal weights are less sensitive to reduced placental weight (and therefore reduced intrauterine space) in early gestation compared to late gestation. However, even in late gestation, mechanisms still exist that maintain fetal growth when the size of the placenta is reduced. One such mechanism is likely to be improved development of the folded placental-epithelial/maternal-epithelial bilayer. Fold depth, and therefore the maternal fetal interactive surface, increases as gestation advances and is greater in placenta from small fetuses. On the fetal side of the placenta, the epithelial bilayer is embedded in stromal tissue. Glycosaminoglycans are major components of stroma, including hyaluronan and heparan sulfate. Hyaluronidases and heparanases are present within placental tissues, and likely play roles in modification of stromal components to facilitate fold development. Glycosaminoglycans are polymers of forms of glucose (glucosamine, glucuronic acid, iduronic acid) suggesting that glycosaminoglycan synthesis may compete with the glucose needs of the developing fetus. Pig conceptuses are fructogenic, such that a substantial portion of glucose transferred from mother to fetus is converted to fructose. Fructose is an intermediate product in the synthesis of glucosamine from glucose, and glucosamine is linked to regulation of trophoblast cell proliferation through regulation of mTOR. These findings suggest a link between glucose, fructose, glucosamine synthesis, GAG production, and placental morphogenesis, but the details of these interactions remain unclear. In addition, recent placental epithelial transcriptome analysis identified several glucose, amino acid, lipid, vitamin, mineral and hormone transporter mechanisms within the placenta. Further elucidation of mechanisms of placental morphogenesis and solute transport could provide clues to improving nutrient transport to the pig fetus, potentially increasing litter size and piglet birth weights." @default.
• W1589818568 created "2016-06-24" @default.
• W1589818568 creator A5010882139 @default.
• W1589818568 creator A5057264851 @default.
• W1589818568 creator A5064935229 @default.
• W1589818568 creator A5086976607 @default.
• W1589818568 date "2014-12-01" @default.
• W1589818568 modified "2023-10-09" @default.
• W1589818568 title "Placental accommodations for transport and metabolism during intra-uterine crowding in pigs" @default.
• W1589818568 cites W1545953723 @default.
• W1589818568 cites W1567359938 @default.
• W1589818568 cites W1593444788 @default.
• W1589818568 cites W182318834 @default.
• W1589818568 cites W1903533569 @default.
• W1589818568 cites W1966809878 @default.
• W1589818568 cites W1973508181 @default.
• W1589818568 cites W1976327885 @default.
• W1589818568 cites W1985520350 @default.
• W1589818568 cites W1988617777 @default.
• W1589818568 cites W1992611563 @default.
• W1589818568 cites W1993263129 @default.
• W1589818568 cites W1998475753 @default.
• W1589818568 cites W2004750204 @default.
• W1589818568 cites W2006752058 @default.
• W1589818568 cites W2007952506 @default.
• W1589818568 cites W2008397828 @default.
• W1589818568 cites W2018272200 @default.
• W1589818568 cites W2018845927 @default.
• W1589818568 cites W2018885135 @default.
• W1589818568 cites W2020631826 @default.
• W1589818568 cites W2020981348 @default.
• W1589818568 cites W2021216564 @default.
• W1589818568 cites W2025958994 @default.
• W1589818568 cites W2026460218 @default.
• W1589818568 cites W2027786827 @default.
• W1589818568 cites W2029190971 @default.
• W1589818568 cites W2030073764 @default.
• W1589818568 cites W2032153850 @default.
• W1589818568 cites W2032503390 @default.
• W1589818568 cites W2034251761 @default.
• W1589818568 cites W2035798906 @default.
• W1589818568 cites W2037662142 @default.
• W1589818568 cites W2038607323 @default.
• W1589818568 cites W2041275445 @default.
• W1589818568 cites W2042350127 @default.
• W1589818568 cites W2043217525 @default.
• W1589818568 cites W2044485297 @default.
• W1589818568 cites W2044828529 @default.
• W1589818568 cites W2044993635 @default.
• W1589818568 cites W2046472576 @default.
• W1589818568 cites W2047336940 @default.
• W1589818568 cites W2050679895 @default.
• W1589818568 cites W2059831201 @default.
• W1589818568 cites W2061070956 @default.
• W1589818568 cites W2061423523 @default.
• W1589818568 cites W2062787020 @default.
• W1589818568 cites W2065016714 @default.
• W1589818568 cites W2067874907 @default.
• W1589818568 cites W2068351003 @default.
• W1589818568 cites W2073297072 @default.
• W1589818568 cites W2075178580 @default.
• W1589818568 cites W2078804827 @default.
• W1589818568 cites W2079622067 @default.
• W1589818568 cites W2081275026 @default.
• W1589818568 cites W2083846408 @default.
• W1589818568 cites W2084418363 @default.
• W1589818568 cites W2084897840 @default.
• W1589818568 cites W2089849109 @default.
• W1589818568 cites W2092979224 @default.
• W1589818568 cites W2096942445 @default.
• W1589818568 cites W2103434781 @default.
• W1589818568 cites W2104818591 @default.
• W1589818568 cites W2108184608 @default.
• W1589818568 cites W2109096406 @default.
• W1589818568 cites W2110165171 @default.
• W1589818568 cites W2116462202 @default.
• W1589818568 cites W2118425381 @default.
• W1589818568 cites W2119200917 @default.
• W1589818568 cites W2131431902 @default.
• W1589818568 cites W2139042446 @default.
• W1589818568 cites W2139807366 @default.
• W1589818568 cites W2142853669 @default.
• W1589818568 cites W2147237906 @default.
• W1589818568 cites W2164359822 @default.
• W1589818568 cites W2165655523 @default.
• W1589818568 cites W216678303 @default.
• W1589818568 cites W2167231581 @default.
• W1589818568 cites W2167534889 @default.
• W1589818568 cites W2170651583 @default.
• W1589818568 cites W2291991915 @default.
• W1589818568 cites W2314127170 @default.
• W1589818568 cites W2332118853 @default.
• W1589818568 cites W2399065453 @default.
• W1589818568 cites W2401506578 @default.
• W1589818568 cites W2404046733 @default.
• W1589818568 cites W2404838420 @default.
• W1589818568 cites W2411810421 @default.
• W1589818568 cites W2416110941 @default.
• W1589818568 cites W2418697104 @default.
• W1589818568 cites W2423690012 @default.

• next