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- W1589906147 abstract "Agents used in the treatment of depressive and anxiety disorders are known to cause sedation and have been associated with falls. However it is not clear whether psychiatric illness itself contributes to the increased risk of falling. This study investigated the association between depressive and anxiety disorders and the risk of falls in a populationbased sample of women living in the community. Depressive and anxiety disorders for the preceding 12-month period were ascertained by clinical interview (SCID-IRJP); current medication use and falling history were selfreported. Participants were classified as fallers if they had fallen to the ground at least twice during the same 12-month period. Current users of antipsychotic medication and mood stabilisers were excluded (n-12) resulting in a sample of 961 women aged 20-93yr (median 53yr. IQR 38-67). Fifty-one women (5%) were classified as fallers. Fallers were older [6l (IQR 51-73) vs. 52(37-66) yr, p=O.001] and more likely to use antidepressants (27% vs.II%, p=<O.001) or benzodiazepines (12% vs. 4%. p = 0.005) than non-fallers. Those with depression (n=lIO) were younger [48 (36-60) vs. 53 (38-68) yr, p=O.OI) and yet more likely to fall (10% vs. 5%. p=0.02). Age-adjusted odds for falling were 2.7-fold greater for women with depression (0R=2.7, 95% CI 1.3-5.5, p=0.007) and this relationship was attenuated after adjusting for antidepressant and benzodiazepine use (OR=2.0,95% CI 0.9-4. I , p=0.07). In contrast, anxiety disorders were not associated with falls, even after adjustment for age, medication use or depression. Depression itself contributed independently to the risk of falling. A similar relationship was not observed in those with anxiety disorders. Further research into the mechanistic factors is warranted." @default.
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- W1589906147 date "2007-09-01" @default.
- W1589906147 modified "2023-09-27" @default.
- W1589906147 title "The association between psychiatric illness and falls: Geelong osteoporosis study" @default.
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