Matches in SemOpenAlex for { <https://semopenalex.org/work/W1590857219> ?p ?o ?g. }
- W1590857219 endingPage "750" @default.
- W1590857219 startingPage "734" @default.
- W1590857219 abstract "Recent investigations on 3D chromatin folding revealed that the eukaryote genomes are both highly compartmentalized and extremely dynamic. This review presents the most recent advances in topological domains' organization of the eukaryote genomes and discusses the relationship to chromatin loop formation. CTCF protein appears as a central factor of these two organization levels having either a strong insulating role at TAD borders, or a weaker architectural role in chromatin loop formation. TAD borders directly impact on chromatin dynamics by restricting contacts within specific genomic portions thus confining chromatin loop formation within TADs. We discuss how sub-TAD chromatin dynamics, constrained into a recently described statistical helix conformation, can produce functional interactions by contact stabilization." @default.
- W1590857219 created "2016-06-24" @default.
- W1590857219 creator A5007093224 @default.
- W1590857219 creator A5048093443 @default.
- W1590857219 creator A5052232643 @default.
- W1590857219 creator A5068924391 @default.
- W1590857219 date "2015-07-27" @default.
- W1590857219 modified "2023-09-27" @default.
- W1590857219 title "Contribution of Topological Domains and Loop Formation to 3D Chromatin Organization" @default.
- W1590857219 cites W1528506800 @default.
- W1590857219 cites W1558882143 @default.
- W1590857219 cites W1945579058 @default.
- W1590857219 cites W1964184081 @default.
- W1590857219 cites W1965863160 @default.
- W1590857219 cites W1966446979 @default.
- W1590857219 cites W1973062929 @default.
- W1590857219 cites W1975702835 @default.
- W1590857219 cites W1975777043 @default.
- W1590857219 cites W1980980040 @default.
- W1590857219 cites W1984340155 @default.
- W1590857219 cites W1984827465 @default.
- W1590857219 cites W1991149014 @default.
- W1590857219 cites W1994536648 @default.
- W1590857219 cites W2002399114 @default.
- W1590857219 cites W2009576540 @default.
- W1590857219 cites W2018658338 @default.
- W1590857219 cites W2024193989 @default.
- W1590857219 cites W2024640399 @default.
- W1590857219 cites W2032140335 @default.
- W1590857219 cites W2032520017 @default.
- W1590857219 cites W2038774969 @default.
- W1590857219 cites W2042930277 @default.
- W1590857219 cites W2047038877 @default.
- W1590857219 cites W2048002474 @default.
- W1590857219 cites W2056482755 @default.
- W1590857219 cites W2064374160 @default.
- W1590857219 cites W2065006553 @default.
- W1590857219 cites W2068906158 @default.
- W1590857219 cites W2070021921 @default.
- W1590857219 cites W2073026107 @default.
- W1590857219 cites W2073504534 @default.
- W1590857219 cites W2074588926 @default.
- W1590857219 cites W2074915491 @default.
- W1590857219 cites W2076154138 @default.
- W1590857219 cites W2078336790 @default.
- W1590857219 cites W2081754347 @default.
- W1590857219 cites W2089894746 @default.
- W1590857219 cites W2090037139 @default.
- W1590857219 cites W2096577969 @default.
- W1590857219 cites W2097798909 @default.
- W1590857219 cites W2099034339 @default.
- W1590857219 cites W2099357999 @default.
- W1590857219 cites W2110174983 @default.
- W1590857219 cites W2117977423 @default.
- W1590857219 cites W2132089243 @default.
- W1590857219 cites W2142860698 @default.
- W1590857219 cites W2142911525 @default.
- W1590857219 cites W2145619687 @default.
- W1590857219 cites W2146070857 @default.
- W1590857219 cites W2148981854 @default.
- W1590857219 cites W2152968621 @default.
- W1590857219 cites W2153747257 @default.
- W1590857219 cites W2157576490 @default.
- W1590857219 cites W2161212572 @default.
- W1590857219 cites W2163605769 @default.
- W1590857219 cites W2170696599 @default.
- W1590857219 cites W2175853567 @default.
- W1590857219 cites W2252885557 @default.
- W1590857219 cites W4300458703 @default.
- W1590857219 doi "https://doi.org/10.3390/genes6030734" @default.
- W1590857219 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4584327" @default.
- W1590857219 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26226004" @default.
- W1590857219 hasPublicationYear "2015" @default.
- W1590857219 type Work @default.
- W1590857219 sameAs 1590857219 @default.
- W1590857219 citedByCount "52" @default.
- W1590857219 countsByYear W15908572192015 @default.
- W1590857219 countsByYear W15908572192016 @default.
- W1590857219 countsByYear W15908572192017 @default.
- W1590857219 countsByYear W15908572192018 @default.
- W1590857219 countsByYear W15908572192019 @default.
- W1590857219 countsByYear W15908572192020 @default.
- W1590857219 countsByYear W15908572192021 @default.
- W1590857219 countsByYear W15908572192022 @default.
- W1590857219 countsByYear W15908572192023 @default.
- W1590857219 crossrefType "journal-article" @default.
- W1590857219 hasAuthorship W1590857219A5007093224 @default.
- W1590857219 hasAuthorship W1590857219A5048093443 @default.
- W1590857219 hasAuthorship W1590857219A5052232643 @default.
- W1590857219 hasAuthorship W1590857219A5068924391 @default.
- W1590857219 hasBestOaLocation W15908572191 @default.
- W1590857219 hasConcept C104317684 @default.
- W1590857219 hasConcept C111936080 @default.
- W1590857219 hasConcept C114614502 @default.
- W1590857219 hasConcept C119599485 @default.
- W1590857219 hasConcept C127413603 @default.
- W1590857219 hasConcept C141231307 @default.
- W1590857219 hasConcept C167227067 @default.