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- W1591196765 abstract "The present study examined changes in retinal tyrosine hydroxylase (TH) expression in rats having undergone optic nerve transection and housed under a normal day/night cycle or in the dark. The aim was to investigate the effects of amacrine cells on axonal regeneration in retinal ganglion cells and on the synapses that transmit visual signals. The results revealed that retinal TH expression gradually decreased following optic nerve transection in rats housed under a normal day/night cycle, reaching a minimum at 5 days. In contrast, retinal TH expression decreased to a minimum at 1 day following optic nerve transection in dark reared rats, gradually increasing afterward and reaching a normal level at 5-7 days. The number of TH-positive synaptic particles correlated with the TH levels, indicating that dark rearing can help maintain TH expression during the synaptic degeneration stage (5-7 days after optic nerve injury) in retinal amacrine cells." @default.
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- W1591196765 date "2012-01-05" @default.
- W1591196765 modified "2023-09-26" @default.
- W1591196765 title "Dark rearing maintains tyrosine hydroxylase expression in retinal amacrine cells following optic nerve transection." @default.
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- W1591196765 doi "https://doi.org/10.3969/j.issn.1673-5374.2012.01.003" @default.
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