FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1591714400> ?p ?o ?g. }

• W1591714400 endingPage "31524" @default.
• W1591714400 startingPage "31518" @default.
• W1591714400 abstract "The Ah receptor (AHR) is a ligand-activated transcription factor that is structurally related to its dimerization partner, the Ah receptor nuclear translocator (ARNT), and two Drosophila proteins, SIM and PER. All four proteins contain a region of homology now referred to as a PAS homology domain. In addition, the AHR, ARNT, and SIM harbor a basic region helix-loop-helix motif in their N termini, whereas PER does not. Previous mapping studies of the AHR have demonstrated that the PAS domain contains sequences required for ligand recognition, dimerization, and interaction with the 90-kDa heat shock protein. They also have confirmed that the basic region helix-loop-helix domain plays a role in both dimerization and sequence-specific DNA binding. To identify domains involved in transactivation of target genes, we generated chimeras of AHR/ARNT deletion mutants with the DNA binding region of the yeast Gal4 protein, transiently expressed these in COS-1 cells, and monitored their capacity to activate the chloramphenicol acetyltransferase reporter gene under the control of a minimal promoter driven by enhancer elements recognized by Gal4. Extensive analysis of these fusions revealed that the AHR and ARNT harbor potent transactivation domains within their C termini. Importantly, the amino-terminal halves of both the AHR and ARNT were found to be devoid of transactivation activity." @default.
• W1591714400 created "2016-06-24" @default.
• W1591714400 creator A5025559430 @default.
• W1591714400 creator A5034581870 @default.
• W1591714400 creator A5070328890 @default.
• W1591714400 creator A5070827775 @default.
• W1591714400 date "1994-12-01" @default.
• W1591714400 modified "2023-10-15" @default.
• W1591714400 title "Potent transactivation domains of the Ah receptor and the Ah receptor nuclear translocator map to their carboxyl termini." @default.
• W1591714400 cites W1505278126 @default.
• W1591714400 cites W1530358119 @default.
• W1591714400 cites W1576236282 @default.
• W1591714400 cites W1748456144 @default.
• W1591714400 cites W1761484484 @default.
• W1591714400 cites W1853332360 @default.
• W1591714400 cites W1958059146 @default.
• W1591714400 cites W1969656285 @default.
• W1591714400 cites W1975712471 @default.
• W1591714400 cites W1979697640 @default.
• W1591714400 cites W1980214543 @default.
• W1591714400 cites W1982265633 @default.
• W1591714400 cites W1989308870 @default.
• W1591714400 cites W1990874048 @default.
• W1591714400 cites W1996454474 @default.
• W1591714400 cites W2006362317 @default.
• W1591714400 cites W2009135996 @default.
• W1591714400 cites W2013087078 @default.
• W1591714400 cites W2017133589 @default.
• W1591714400 cites W2025403108 @default.
• W1591714400 cites W2033777731 @default.
• W1591714400 cites W2037653294 @default.
• W1591714400 cites W2040734916 @default.
• W1591714400 cites W2059185804 @default.
• W1591714400 cites W2062589966 @default.
• W1591714400 cites W2063751484 @default.
• W1591714400 cites W2064209430 @default.
• W1591714400 cites W2071198735 @default.
• W1591714400 cites W2075496313 @default.
• W1591714400 cites W2087332917 @default.
• W1591714400 cites W2088622701 @default.
• W1591714400 cites W2092938366 @default.
• W1591714400 cites W2093897768 @default.
• W1591714400 cites W2103735500 @default.
• W1591714400 cites W2105014300 @default.
• W1591714400 cites W2127167523 @default.
• W1591714400 cites W2129972061 @default.
• W1591714400 cites W2138270253 @default.
• W1591714400 cites W2144206181 @default.
• W1591714400 cites W2159511823 @default.
• W1591714400 cites W2167721895 @default.
• W1591714400 cites W2185873493 @default.
• W1591714400 cites W4236512674 @default.
• W1591714400 cites W4248369960 @default.
• W1591714400 cites W4705614 @default.
• W1591714400 doi "https://doi.org/10.1016/s0021-9258(18)31725-3" @default.
• W1591714400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7989319" @default.
• W1591714400 hasPublicationYear "1994" @default.
• W1591714400 type Work @default.
• W1591714400 sameAs 1591714400 @default.
• W1591714400 citedByCount "152" @default.
• W1591714400 countsByYear W15917144002012 @default.
• W1591714400 countsByYear W15917144002013 @default.
• W1591714400 countsByYear W15917144002014 @default.
• W1591714400 countsByYear W15917144002015 @default.
• W1591714400 countsByYear W15917144002016 @default.
• W1591714400 countsByYear W15917144002018 @default.
• W1591714400 countsByYear W15917144002019 @default.
• W1591714400 countsByYear W15917144002020 @default.
• W1591714400 countsByYear W15917144002021 @default.
• W1591714400 countsByYear W15917144002022 @default.
• W1591714400 countsByYear W15917144002023 @default.
• W1591714400 crossrefType "journal-article" @default.
• W1591714400 hasAuthorship W1591714400A5025559430 @default.
• W1591714400 hasAuthorship W1591714400A5034581870 @default.
• W1591714400 hasAuthorship W1591714400A5070328890 @default.
• W1591714400 hasAuthorship W1591714400A5070827775 @default.
• W1591714400 hasBestOaLocation W15917144001 @default.
• W1591714400 hasConcept C104317684 @default.
• W1591714400 hasConcept C1292079 @default.
• W1591714400 hasConcept C170493617 @default.
• W1591714400 hasConcept C185592680 @default.
• W1591714400 hasConcept C203014093 @default.
• W1591714400 hasConcept C2776791281 @default.
• W1591714400 hasConcept C2776914184 @default.
• W1591714400 hasConcept C55493867 @default.
• W1591714400 hasConcept C63932345 @default.
• W1591714400 hasConcept C71240020 @default.
• W1591714400 hasConcept C86339819 @default.
• W1591714400 hasConcept C86803240 @default.
• W1591714400 hasConcept C87753298 @default.
• W1591714400 hasConceptScore W1591714400C104317684 @default.
• W1591714400 hasConceptScore W1591714400C1292079 @default.
• W1591714400 hasConceptScore W1591714400C170493617 @default.
• W1591714400 hasConceptScore W1591714400C185592680 @default.
• W1591714400 hasConceptScore W1591714400C203014093 @default.
• W1591714400 hasConceptScore W1591714400C2776791281 @default.
• W1591714400 hasConceptScore W1591714400C2776914184 @default.
• W1591714400 hasConceptScore W1591714400C55493867 @default.

• next