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- W1591888892 abstract "The chapter offers information on dementia with Lewy bodies and Parkinson's disease dementia. Neurodegeneration associated with abnormal alpha-synuclein metabolism and Lewy body (LB) formation may present as a variety of clinical syndromes depending on the distribution of pathologic changes and neurochemical disruption. Dementia with Lewy bodies (DLB) and Parkinson's disease (PD) are the two most commonly recognized manifestations of LB disease and the close association between them has only been recognized in the past decade. DLB is thought to account for up to 20% of all elderly cases of dementia reaching autopsy, with a clinical presentation primarily characterized by cognitive decline leading to dementia, accompanied in the majority of cases (∼75%) by extrapyramidal motor features and additional neuropsychiatric features. Parkinson's disease dementia (PDD) starts by contrast with extrapyramidal motor symptoms with the later onset of cognitive decline and psychiatric symptoms, progressing in many cases to a clinical and pathologic endpoint, which is largely indistinguishable from DLB. Distinction between DLB and PDD is based on the temporal sequence in which symptoms appear with the recommendation that PDD should be diagnosed if extrapyramidal motor features have been present for a year or more before cognitive decline is noted. Cholinesterase inhibitors (CHEIs) offer the greatest hope for symptomatic improvement in both psychotic and cognitive features of DLB and PDD at present and seem to offer these benefits without significant compromise of motor function." @default.
- W1591888892 created "2016-06-24" @default.
- W1591888892 creator A5003002074 @default.
- W1591888892 date "2007-01-01" @default.
- W1591888892 modified "2023-09-26" @default.
- W1591888892 title "Chapter 9 Dementia with Lewy Bodies and Parkinson's Disease Dementia" @default.
- W1591888892 cites W1530469809 @default.
- W1591888892 cites W1537807811 @default.
- W1591888892 cites W1564397321 @default.
- W1591888892 cites W1765690683 @default.
- W1591888892 cites W1884672048 @default.
- W1591888892 cites W1963931649 @default.
- W1591888892 cites W1964540847 @default.
- W1591888892 cites W1964593020 @default.
- W1591888892 cites W1965577994 @default.
- W1591888892 cites W1966264626 @default.
- W1591888892 cites W1966775956 @default.
- W1591888892 cites W1967114240 @default.
- W1591888892 cites W1969820784 @default.
- W1591888892 cites W1969895941 @default.
- W1591888892 cites W1971135544 @default.
- W1591888892 cites W1973652068 @default.
- W1591888892 cites W1974590920 @default.
- W1591888892 cites W1975837564 @default.
- W1591888892 cites W1976103627 @default.
- W1591888892 cites W1979915207 @default.
- W1591888892 cites W1981397017 @default.
- W1591888892 cites W1985023593 @default.
- W1591888892 cites W1985563672 @default.
- W1591888892 cites W1987467412 @default.
- W1591888892 cites W1993415722 @default.
- W1591888892 cites W1996881496 @default.
- W1591888892 cites W1997505208 @default.
- W1591888892 cites W1999443209 @default.
- W1591888892 cites W2000629464 @default.
- W1591888892 cites W2001644256 @default.
- W1591888892 cites W2002671775 @default.
- W1591888892 cites W2004500341 @default.
- W1591888892 cites W2004928043 @default.
- W1591888892 cites W2007782200 @default.
- W1591888892 cites W2009501519 @default.
- W1591888892 cites W2011580750 @default.
- W1591888892 cites W2011849432 @default.
- W1591888892 cites W2013877860 @default.
- W1591888892 cites W2014300038 @default.
- W1591888892 cites W2014513813 @default.
- W1591888892 cites W2016001317 @default.
- W1591888892 cites W2016476570 @default.
- W1591888892 cites W2018773132 @default.
- W1591888892 cites W2018963680 @default.
- W1591888892 cites W2019215143 @default.
- W1591888892 cites W2019820338 @default.
- W1591888892 cites W2020125528 @default.
- W1591888892 cites W2022541036 @default.
- W1591888892 cites W2022550698 @default.
- W1591888892 cites W2023659715 @default.
- W1591888892 cites W2023785308 @default.
- W1591888892 cites W2029012009 @default.
- W1591888892 cites W2030602873 @default.
- W1591888892 cites W2036957987 @default.
- W1591888892 cites W2036999485 @default.
- W1591888892 cites W2037088901 @default.
- W1591888892 cites W2038447514 @default.
- W1591888892 cites W2039294533 @default.
- W1591888892 cites W2040753345 @default.
- W1591888892 cites W2041834073 @default.
- W1591888892 cites W2049683617 @default.
- W1591888892 cites W2053071049 @default.
- W1591888892 cites W2059147823 @default.
- W1591888892 cites W2062055770 @default.
- W1591888892 cites W2065446074 @default.
- W1591888892 cites W2069080061 @default.
- W1591888892 cites W2069147136 @default.
- W1591888892 cites W2070495958 @default.
- W1591888892 cites W2072579944 @default.
- W1591888892 cites W2073449985 @default.
- W1591888892 cites W2074085250 @default.
- W1591888892 cites W2074808213 @default.
- W1591888892 cites W2074984806 @default.
- W1591888892 cites W2075960947 @default.
- W1591888892 cites W2076254379 @default.
- W1591888892 cites W2079579974 @default.
- W1591888892 cites W2079645363 @default.
- W1591888892 cites W2082276412 @default.
- W1591888892 cites W2083221352 @default.
- W1591888892 cites W2083495334 @default.
- W1591888892 cites W2085397388 @default.
- W1591888892 cites W2086156255 @default.
- W1591888892 cites W2087485448 @default.
- W1591888892 cites W2088086626 @default.
- W1591888892 cites W2088919930 @default.
- W1591888892 cites W2091327537 @default.
- W1591888892 cites W2095529296 @default.
- W1591888892 cites W2095602923 @default.
- W1591888892 cites W2101150488 @default.
- W1591888892 cites W2102572922 @default.
- W1591888892 cites W2107365570 @default.
- W1591888892 cites W2108410348 @default.