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- W1591924770 abstract "BackgroundSonographic aspects of prenatally diagnosed cleft-lip were reviewed and compared with postnatal findings.Method38 cases of prenatally diagnosed fetal cleft lip were reviewed and the following was recorded: gestational age at diagnosis, maternal age, malformation history, associated palate clift, associated aneuploidies and malformations and postnatal follow-up. Kariotyping was performed in all cases.ResultsMaternal age was 28.37 years and only one case had history of cleft lip. Gestational age at diagnosis was 28 weeks. Isolated cleft lip were observed in 7 cases (18.42%): 5 fetuses (71.43%) with left lesion and 2 (28.57%) with right lesion. One case (2.63%) was associated with cleft palate. Aneuploidy associated with structural malformations was identified in 9 cases (23.68%): trissomy 13 (n = 6); trissomy 18 (n = 2) and 47XXY (n = 1) In 66% of those cases associated cleft palate was found. Associated malformations with normal karyotype were found in 22 cases with associated cleft palate in 50% of those cases.ConclusionIn this series, fetal cleft lips were frequently associated with structural malformations and cromossomal, especially when cleft palate was associated. Cleft lip is an indication for fetal karyotyping and associated malformations must be discarded by level three ultra-sound scan." @default.
- W1591924770 created "2016-06-24" @default.
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- W1591924770 date "2000-10-01" @default.
- W1591924770 modified "2023-09-27" @default.
- W1591924770 title "F104Prenatal diagnosis and follow-up of 38 cases of cleft lip - 5-year experience of a Brazilian specialized center" @default.
- W1591924770 doi "https://doi.org/10.1046/j.1469-0705.2000.00015-1-103.x" @default.
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