Matches in SemOpenAlex for { <https://semopenalex.org/work/W1592164162> ?p ?o ?g. }
- W1592164162 endingPage "42" @default.
- W1592164162 startingPage "32" @default.
- W1592164162 abstract "Reactive oxygen species (ROS), such as superoxide, hydrogen peroxide (H2O2), and hydroxyl radical, have for a long time been considered as accidental by-products of respiratory energy production in mitochondria and as being useless and rather deleterious to biological systems. Contrary to such a classical view, accumulating evidence indicates that upon stimulation of divergent receptor systems, ROS are intentionally produced and even required for appropriate signal transduction and biological responses. Work by our group and that of others have shown that stimulation of mast cells through the high-affinity IgE receptor (FcεRI) induces the production of ROS such as superoxide and H2O2 possibly by the phagocyte NADPH oxidase homologue and that these endogenously produced oxidants have important functions in regulation of various mast cell responses, including degranulation, leukotriene secretion, and cytokine production. Subsequent studies have defined particular biochemical pathways that can be targeted by ROS and/or cellular redox balance. More recent research reveals that ROS may also play an important role in mast cell activation by divergent allergy-relevant environmental substances, for instance heavy metals and polycyclic aromatic hydrocarbons. This review summarizes current knowledge on the role of endogenous oxidants in mast cell activation." @default.
- W1592164162 created "2016-06-24" @default.
- W1592164162 creator A5001389064 @default.
- W1592164162 creator A5007909935 @default.
- W1592164162 creator A5031542615 @default.
- W1592164162 creator A5042186784 @default.
- W1592164162 creator A5068179878 @default.
- W1592164162 date "2005-01-01" @default.
- W1592164162 modified "2023-09-27" @default.
- W1592164162 title "Role of Oxidants in Mast Cell Activation" @default.
- W1592164162 cites W1503586314 @default.
- W1592164162 cites W1555703707 @default.
- W1592164162 cites W1599249369 @default.
- W1592164162 cites W1614231230 @default.
- W1592164162 cites W1618519163 @default.
- W1592164162 cites W1734082729 @default.
- W1592164162 cites W1945380293 @default.
- W1592164162 cites W1969236715 @default.
- W1592164162 cites W1972613209 @default.
- W1592164162 cites W1996338594 @default.
- W1592164162 cites W2000087274 @default.
- W1592164162 cites W2001361664 @default.
- W1592164162 cites W2014124696 @default.
- W1592164162 cites W2017668832 @default.
- W1592164162 cites W2029652412 @default.
- W1592164162 cites W2033330205 @default.
- W1592164162 cites W2033606609 @default.
- W1592164162 cites W2044624672 @default.
- W1592164162 cites W2048569323 @default.
- W1592164162 cites W2050337090 @default.
- W1592164162 cites W2058461613 @default.
- W1592164162 cites W2058989790 @default.
- W1592164162 cites W2059299508 @default.
- W1592164162 cites W2059534402 @default.
- W1592164162 cites W2061575199 @default.
- W1592164162 cites W2064636154 @default.
- W1592164162 cites W2086485349 @default.
- W1592164162 cites W2100165609 @default.
- W1592164162 cites W2101745219 @default.
- W1592164162 cites W2102619095 @default.
- W1592164162 cites W2119256134 @default.
- W1592164162 cites W2121420563 @default.
- W1592164162 cites W2140237511 @default.
- W1592164162 cites W2140676951 @default.
- W1592164162 cites W2143489424 @default.
- W1592164162 cites W2157579772 @default.
- W1592164162 cites W2162537991 @default.
- W1592164162 cites W2169982907 @default.
- W1592164162 cites W2173762551 @default.
- W1592164162 cites W2399303500 @default.
- W1592164162 doi "https://doi.org/10.1159/000087569" @default.
- W1592164162 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16107761" @default.
- W1592164162 hasPublicationYear "2005" @default.
- W1592164162 type Work @default.
- W1592164162 sameAs 1592164162 @default.
- W1592164162 citedByCount "82" @default.
- W1592164162 countsByYear W15921641622012 @default.
- W1592164162 countsByYear W15921641622013 @default.
- W1592164162 countsByYear W15921641622014 @default.
- W1592164162 countsByYear W15921641622015 @default.
- W1592164162 countsByYear W15921641622016 @default.
- W1592164162 countsByYear W15921641622017 @default.
- W1592164162 countsByYear W15921641622018 @default.
- W1592164162 countsByYear W15921641622019 @default.
- W1592164162 countsByYear W15921641622020 @default.
- W1592164162 countsByYear W15921641622021 @default.
- W1592164162 countsByYear W15921641622022 @default.
- W1592164162 countsByYear W15921641622023 @default.
- W1592164162 crossrefType "book-chapter" @default.
- W1592164162 hasAuthorship W1592164162A5001389064 @default.
- W1592164162 hasAuthorship W1592164162A5007909935 @default.
- W1592164162 hasAuthorship W1592164162A5031542615 @default.
- W1592164162 hasAuthorship W1592164162A5042186784 @default.
- W1592164162 hasAuthorship W1592164162A5068179878 @default.
- W1592164162 hasConcept C170493617 @default.
- W1592164162 hasConcept C181199279 @default.
- W1592164162 hasConcept C185592680 @default.
- W1592164162 hasConcept C203014093 @default.
- W1592164162 hasConcept C2778175917 @default.
- W1592164162 hasConcept C2779719074 @default.
- W1592164162 hasConcept C2779726688 @default.
- W1592164162 hasConcept C2780795997 @default.
- W1592164162 hasConcept C28859421 @default.
- W1592164162 hasConcept C48349386 @default.
- W1592164162 hasConcept C49802076 @default.
- W1592164162 hasConcept C55493867 @default.
- W1592164162 hasConcept C62478195 @default.
- W1592164162 hasConcept C86803240 @default.
- W1592164162 hasConcept C95444343 @default.
- W1592164162 hasConceptScore W1592164162C170493617 @default.
- W1592164162 hasConceptScore W1592164162C181199279 @default.
- W1592164162 hasConceptScore W1592164162C185592680 @default.
- W1592164162 hasConceptScore W1592164162C203014093 @default.
- W1592164162 hasConceptScore W1592164162C2778175917 @default.
- W1592164162 hasConceptScore W1592164162C2779719074 @default.
- W1592164162 hasConceptScore W1592164162C2779726688 @default.
- W1592164162 hasConceptScore W1592164162C2780795997 @default.
- W1592164162 hasConceptScore W1592164162C28859421 @default.