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- W1592562030 abstract "Abstract A study was made of the histologic changes occurring in the long bones and the alveolar bone of rats maintained on a tryptophan-deficient diet for periods of time varying from three to twenty-six weeks. A narrowing and premature closure of the epiphyseal plate were noted after five weeks on the deficient diet. This closure prevented further growth of the animal. The osteoporosis of the long bones was progressive in nature, becoming intense in those animals on the deficient diet for sixteen to twenty-six weeks. There was a gradual replacement of the myeloid elements of the marrow spaces by fatty tissues. The osteoporosis of the spongiosa of the alveolar bone was a constant finding. As a result of this osteoporosis, the bone was unable to cope with the normal stresses usually imposed upon it, leading to secondary occlusal trauma." @default.
- W1592562030 created "2016-06-24" @default.
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- W1592562030 date "1956-03-01" @default.
- W1592562030 modified "2023-09-26" @default.
- W1592562030 title "Effect of tryptophan deficiency on bones and teeth of rats" @default.
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- W1592562030 doi "https://doi.org/10.1016/0030-4220(56)90009-3" @default.
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