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- W1592787405 abstract "A personal recollection is provided on my research, aiming to develop various stable-isotope aided NMR methods for amino acids, peptides, and proteins. A salient trait of our approaches is to extensively use NMR samples composed of site – and stereospecifically isotope-labeled components, which can be prepared by microbial fermentations, enzyme-catalyzed reactions, and chiral organic syntheses – all areas in which Japan leads the world. The selective 13C, 15N-double labeling method and the stereo-array isotope labeling (SAIL) method have been chosen as representatives of my early and latest work, respectively, to illustrate the features of our approaches.Keywords:isotope-aided NMR methods;selective 13C, 15N-double labeling;Streptomyces subtilisin inhibitor (S-SI);stereospecific deuteration;stereo-array isotope labeling (SAIL) method" @default.
- W1592787405 created "2016-06-24" @default.
- W1592787405 creator A5076485810 @default.
- W1592787405 date "2012-06-15" @default.
- W1592787405 modified "2023-09-26" @default.
- W1592787405 title "Kainosho, Masatsune: Developing Stable-Isotope- Aided NMR Technologies for Biological Systems" @default.
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- W1592787405 doi "https://doi.org/10.1002/9780470034590.emrhp1026" @default.
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