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- W1592994844 abstract "Interaction of rabbit antibody to L cell lines caused an intense stimulation of radioactive nucleoside uptake which was maximal 24–72 hr after exposure to antibody. Smaller but parallel increases in DNA synthesis, cell growth rate, and numbers were observed. A marked dose dependency was observed with smaller amounts of antisera being stimulatory and larger doses cytotoxic. The stimulatory antibody was demonstrated to be present in the IgG globulin fraction. The IgG antibody was rapidly cytotoxic to target cells in the presence of fresh exogenous complement. Prolonged trypsinization of L cells reduced the ability of the cells to be stimulated by anti-L antiserum presumably due to removal of membrane antigens." @default.
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- W1592994844 date "1975-06-01" @default.
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- W1592994844 title "Humoral immunostimulation" @default.
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- W1592994844 doi "https://doi.org/10.1016/s0008-8749(75)80049-9" @default.
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