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- W1593333265 abstract "Abstract 1. 1. Clinical, biochemical and cytological findings in a patient with gametogenic precocity studied for 5 months, from age 9.5 months to 14.5 months, are presented. The diagnosis of true constitutional precocious puberty was established in this patient by the evidence presented. To the authors' knowledge, this is the youngest patient with proved ovulatory gametogenesis reported to date. 2. 2. The differential diagnosis of patients with precocious sexual development and uterine bleeding has been considered. 3. 3. Diagnostic laparotomy in the absence of a palpable adnexal mass has again been discouraged. 4. 4. Endometrial biopsy has been discussed and endorsed as a useful adjunct in the diagnostic evaluation of such patients. Proff of ovulatory menses by endometrial biopsy indicated complete precocious puberty in this patient, and the absence of abnormal neurological findings indicated it was of the idiopathic type." @default.
- W1593333265 created "2016-06-24" @default.
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- W1593333265 date "1965-02-01" @default.
- W1593333265 modified "2023-09-27" @default.
- W1593333265 title "Gametogenic precocity in a twelve-month-old female" @default.
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- W1593333265 doi "https://doi.org/10.1016/0002-9378(65)90118-3" @default.
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