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• W1593580245 abstract "Mycobacterium tuberculosis, the causative agent of tuberculosis, poses a global health challenge due to the emergence of drug-resistant strains. Recently, bacterial energy metabolism has come into focus as a promising new target pathway for the development of antimycobacterial drugs. This review summarizes our current knowledge on mycobacterial respiratory energy conversion, in particular, during the physiologically dormant state that is associated with latent or persistent tuberculosis infections. Targeting components of respiratory ATP production, such as type-2 NADH dehydrogenase or ATP synthase, is illustrated as an emerging strategy in the development of novel drugs." @default.
• W1593580245 created "2016-06-24" @default.
• W1593580245 creator A5044159335 @default.
• W1593580245 creator A5058620722 @default.
• W1593580245 date "2010-03-20" @default.
• W1593580245 modified "2023-10-01" @default.
• W1593580245 title "Respiratory ATP synthesis: the new generation of mycobacterial drug targets?" @default.
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• W1593580245 doi "https://doi.org/10.1111/j.1574-6968.2010.01959.x" @default.
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